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Models

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Mice

a-IRES-Cre

Strain Name：C57BL/6Smoc-atm1(Cre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200027

A IRES-Cre expression cassette was knocked into the a gene stop codon site via ESC targeting. Male mice with a germline Cre leak expression condition, please use female mice and flox mice for breeding crosses. References are available, please see the website for details.

Mice

Ces1(a-h)-KO

Strain Name：C57BL/6Smoc-Ces1(a-h)em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-241031

The exon1-exon14 of Ces1(a-h) gene was deleted to generate Ces1(a-h) knockout mouse.

Mice

Ces1(a-h)-KO/Apoc3-pAlb-hCES1

Strain Name：C57BL/6Smoc-Ces1aem1Apoc3tm1(pAlb-hCES1-3'UTR-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-XA-250706

The Ces1(a-h)-KO(NM-KO-241031) was crossed with Apoc3-pAlb-hCES1(NM-KI-241030) to generate Ces1a-KO/Apoc3-pAlb-hCES1-3'UTR mice.

Mice

MHC ClassII(I-A/I-E)-KO(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1H2-Ab1em1H2-Aaem1H2-Eb1em1H2-Eb2em1H2-Ea-ps em1Smoc
Strain State：Developing | Cat. NO.：NM-NSG-003

All sequences from the upstream of  mouse H2-Ab1 gene exon 2  to the upstream of the H2-Ea-ps gene  exon 1 were knocked out to obtain H2-Ab1、H2-Aa、H2-Eb1、H2-Eb2、H2-Ea-ps knockout mouse models.  These MHC class II molecule-deficient mice were on the NMG genetic background and also lacked cell surface expression of both class II-A and class II-E MHC proteins.

Mice

MHC Class II(I-A/I-E)-KO(Nod-Scid)

Strain Name：NOD-PrkdcscidH2-Ab1em1H2-Aaem1H2-Eb1em1H2-Eb2em1H2-Ea-psem1Smoc
Strain State：Developing | Cat. NO.：NM-KO-18057

All sequences from the upstream of mouse H2-Ab1 gene exon 2 to the upstream of the H2-Ea-ps gene exon 1 were knocked out to obtain H2-Ab1、H2-Aa、H2-Eb1、H2-Eb2、H2-Ea-ps knockout mouse models. These MHC class II molecule-deficient mice were on the Nod-Scid genetic background and lacked cell surface expression of both class II-A and class II-E MHC proteins.

Mice

MHC Class II (I-A/I-E) -KO

Strain Name：C57BL/6Smoc-H2-Ab1em1H2-Aaem1 H2-Eb1em1H2-Eb2em1H2-Ea-ps em1 Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18032

All sequences from the upstream of mouse H2-Ab1 gene exon 2 to the upstream of the H2-Ea-ps gene exon 1 were knocked out to obtain H2-Ab1、H2-Aa、H2-Eb1、H2-Eb2、H2-Ea-ps knockout mouse models. These MHC class II molecule-deficient mice were on the C57BL/6J genetic background and also lacked cell surface expression of both class II-A and class II-E MHC proteins.

Mice

Scn1a-c.473+5G>A

Strain Name：C57BL/6Smoc-Scn1aem1(c.473+5G>A)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-210417

These mice carry a c.473+5G>A mutation of Scn1a gene.

Mice

hHLA-DPA1*03: 01

Strain Name：C57BL/6Smoc-H2-Aaem1（hHLA-DPA1*03: 01）/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210009

The endogenous mice H2-Aa gene was replaced by human HLA-DPA1*03: 01 gene

Mice

Adra2b-KO

Strain Name：C57BL/6Smoc-Adra2Bem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190635

Exon 1 of Adra2b gene was deleted to generate Adra2b knockout mice.

Mice

Adora3-Flox

Strain Name：C57BL/6Smoc-Adora3em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-210056

These mice carry loxP sites flanking exon 2 of Adora3 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Adora3 gene.

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