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Models

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Mice

Fcgr2b-Fcgr3-Fcgr4-KO/hPD-1/hCTLA-4

Strain Name：C57BL/6Smoc-Fcgr2bem1Fcgr3em1Fcgr4em1Pdcd1em1(hPDCD1)Ctla4em1(hCTLA4)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-220070

The Fcgr2b-Fcgr3-Fcgr4-KO/hPD-1/hCTLA4 mouse model was obtained by deleting sequences from upstream of Fcgr3 gene to the 3'UTR of Fcgr2b gene in the hPD-1/hCTLA4(NM-HU-00079) mouse.

Mice

hPD-1/hCTLA-4(BALB/c)

Strain Name：BALB/cAnSmoc-Pdcd1tm1(hPDCD1)Ctla4tm1(hCTLA4)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200277
Validation Data：Presence

hPD-1(NM-HU-190079) was crossed with hCTLA4(2)(NM-HU-190078)to generate hPD-1/hCTLA4 mice

Mice

hIL2/hIL2RB/hIL2RG

Strain Name：C57BL/6Smoc-Il2rgtm1(IL2RG)Il2tm3(hIL2)Il2rbtm1(hIL2RB)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220145

hIL2RG(NM-HU-200007) and IL2RB(NM-HU-2000055) mice were crossed with hIL2(NM-HU-190048) mice to generate hIL2/hIL2RB/hIL2RG mice.

Mice

Mecp2-Flox

Strain Name：C57BL/6Smoc-Mecp2tm2(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-190001

These mice carry loxP sites flanking exon 2-3. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

Aasdh-Flox

Strain Name：C57BL/6Smoc-Aasdhem1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-253924

These mice carry loxP sites flanking exon 5 of Aasdh gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aasdh gene.

Mice

Aak1-KO

Strain Name：C57BL/6Smoc-Aak1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200002

Exon 3 of Aak1 gene was deleted to generate Aak1 knockout mice.

Mice

Il6-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il6em1(Luc-eGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00011
Publications：1piece

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il6.

Mice

hADAM17

Strain Name：C57BL/6Smoc-Adam17tm(hADAM17)Smoc
Strain State：Developing | Cat. NO.：NM-HU-220260

The endogenous mouse Adam17 gene was replaced by human ADAM17 gene.

Mice

Aadacl4-Flox

Strain Name：C57BL/6Smoc-Aadacl4em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-253846

These mice carry loxP sites flanking exon 2-3 of Aadacl4 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aadacl4 gene.

Mice

Nos1-CreERT2

Strain Name：C57BL/6Smoc-Nos1em1(CreERT2-SV40polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200091
Validation Data：Presence

A CreERT2-SV40polyA expression cassette was knocked into the Nos1 gene start codon site.

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