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Models

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Mice

MHCII/B2m-KO(NMG)

Strain Name：NOD.Cg-PrkdcscidIl2rgem1H2-Ab1em1H2-Aaem1H2-Eb1em1H2-Eb2em1H2-Ea-ps em1B2m em1Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-014

All sequences from the upstream of  mouse H2-Ab1 gene exon 2  to the upstream of the H2-Ea-ps gene  exon 1 were knocked out to obtain H2-Ab1、H2-Aa、H2-Eb1、H2-Eb2、H2-Ea-ps knockout mouse models.Also, B2m gene was knocked out. These MHC class I and II molecule-deficient mice were on the NMG genetic background and also lacked cell surface expression of both class II-A and class II-E MHC proteins and B2m of class I.

Mice

Aadacl2Fm1-KO

Strain Name：C57BL/6Smoc-Aadacl2Fm1em1Smoc
Strain State：Developing | Cat. NO.：TBD

Exon 5 of Aadacl2Fm1 gene was deleted to generate Aadacl2Fm1 knockout mice.

Mice

AA465934-Flox

Strain Name：C57BL/6Smoc-AA465934em1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of AA465934 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of AA465934 gene.

Mice

Aacs-KO

Strain Name：C57BL/6Smoc-Aacsem1Smoc
Strain State：Developing | Cat. NO.：TBD

Exon 2 of Aacs gene was deleted to generate Aacs knockout mice.

Mice

H2/H2-D1-KO(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1h2em1H2-D1em1Smoc
Strain State：Developing | Cat. NO.：NM-NSG-005

Exon 1-6 of H2;H2-D1 gene was deleted to generate H2;H2-D1 knockout mice.

Mice

Aadat-Flox

Strain Name：C57BL/6Smoc-Aadatem1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of Aadat gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aadat gene.

Mice

Aak1-Flox

Strain Name：C57BL/6Smoc-Aak1em1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of Aak1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aak1 gene.

Mice

Aacs-Flox

Strain Name：C57BL/6Smoc-Aacsem1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of Aacs gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aacs gene.

Mice

Aagab-Flox

Strain Name：C57BL/6Smoc-Aagabem1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of Aagab gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aagab gene.

Mice

Aadacl2fm1-Flox

Strain Name：C57BL/6Smoc-Aadacl2fm1em1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of Aadacl2fm1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aadacl2fm1 gene.

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