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Models

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Mice

C4b-KO

Strain Name：C57BL/6Smoc-C4bem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190761

Exon 3 of C4b gene was deleted to generate C4b knockout mice.

Mice

hCXCR4

Strain Name：C57BL/6Smoc-Cxcr4em1(hCXCR4)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000081

The endogenous mouse Cxcr4 gene was replaced by human CXCR4 gene.

Mice

hCD3EDG(BALB/c)

Strain Name：BALB/c-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)/CbSmoc
Strain State：Repository Live | Cat. NO.：NM-HU-220122

The endogenous mouse Cd3e/Cd3d/Cd3g genes were replaced by human CD3E/CD3D/CD3G gene.

Mice

Bmal1-Flox

Strain Name：C57BL/6Smoc-Bmal1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200063

These mice carry loxP sites flanking exon 8 of Bmal1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Bmal1 gene.

Mice

hCD73(2)

Strain Name：C57BL/6Smoc-Nt5etm3(NT5E)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200009

The endogenous mouse Nt5e gene was replaced by human NT5E gene.

Mice

Il17a-2A-CreERT2

Strain Name：C57BL/6Smoc-Il17aem1(2A-CreERT2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00059

A 2A-Cre cassette was inserted before stop codon of mouse Il17a gene which is known as a T cell marker.

Mice

hHER3(2)

Strain Name：C57BL/6Smoc-Erbb3tm1(hERBB3)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-225068

The endogenous mouse Erbb3 gene was replaced by human ERBB3 gene.

Mice

R26-CAG-2xKRAB-dCas9-IRES-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-Loxp-2xKRAB-dCas9-IRES-EGFP)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-18007

These mice harbor a CAG-LSL-2xKRAB-dCas9-IRES-EGFP-WPRE-pA conditional expression cassette in mouse Rosa26 loci via homologous recombination. This strain can be used in CRISPR mediated target gene transcriptional inhibition (CRISPRi). The loxp-stop-loxp cassette was deleted.

Mice

Casp8-Flox

Strain Name：C57BL/6Smoc-Casp8em1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-190003

These Casp8 flox mice possess loxP sites flanking exons 4. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

Apc-Flox

Strain Name：C57BL/6Smoc-Apctm2(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-200013

These mice carry loxP sites flanking exon 15 of Apc gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Apc gene.

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