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Models

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Mice

Ins2-C96Y

Strain Name：C57BL/6Smoc-Ins2em3(C96Y)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190096

These mice carry a p.C96Y mutation of Ins2 gene.

Mice

Tigre-TetO-hEGFR*del19-IRES-GFP-2A-Cre

Strain Name：C57BL/6Smoc-Igs7em1(tetO-EGFR-del19-IRES-GFP-2A-Cre)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200258

A tetO-EGFR-del19-IRES-GFP-2A-Cre expression cassette was knocked into the TIGRE locus.

Mice

hSPP1

Strain Name：C57BL/6Smoc-Spp1tm1(hSPP1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-225037

The endogenous mouse Spp1 gene was replaced by human SPP1 gene.

Mice

Gad2-IRES-Cre

Strain Name：C57BL/6Smoc-Gad2em1(IRES-iCre-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200078

A IRES-iCre-pA expression cassette was knocked into the Gad2 gene stop codon site.

Mice

hIL11RA

Strain Name：C57BL/6Smoc-Il11ra1tm1(hIL11RA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-204982

The endogenous mice Il11ra1 gene was replaced by human IL11RA gene.

Mice

hTROP2

Strain Name：C57BL/6Smoc-Tacstd2em(hTACSTD2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-215022

The endogenous mice Tacstd2 gene was replaced by human TACSTD2 gene.

Mice

Dmd-Q995X

Strain Name：C57BL/6Smoc-Dmdem1(Q995X)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18026

These mice carry a p.Q995X mutation in Dmd gene.

Mice

hSIRPA/hCD47(BALB/c)

Strain Name：BALB/cAnSmoc-Sirpatm4(hSIRPA)/SmocCd47em1(hCD47)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210020

hCD47 (NM-HU-00050) and hSRPA(2)(NM-HU-18015) were bred with BALB/c mice respectively to generate hSIRPA/hCD47(BALB/c) mice.

Mice

hPD-L1/hSEMA4D

Strain Name：C57BL/6Smoc-Cd274em1(hPD-L1)Sema4dem1(hSemA4D)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190034

hPD-L1(NM-HU-00062) was crossed with hSEMA4D(NM-HU-00117) to generate hPD-L1/hSEMA4D.

Mice

Bhlha15-CreERT2

Strain Name：C57BL/6Smoc-Bhlha15em1(CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200080

The coding region of Bhlha15 gene was replaced by a CreERT2 expression cassette.Besides,a kozak-CreERT2-WPRE-polyA expression cassette were knock into the Bhlha15 gene start codon site to generate Bhlha15-CreERT2(2)(Stock No. NM-KI-200158) mice. Bhlha15(basic helix-loop-helix family member a15) is also known as Mist1. The gene product is involved in controlling exocrine secretion from the pancreas, small intestine and stomach. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Bhlha15.

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