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Models

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Mice

hIL4/hIL4R

Strain Name：C57BL/6Smoc-Il4tm3(hIL4)Il4ratm1(hIL4R)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000106
Validation Data：Presence

These mice are obtained through breeding of two single gene humanized mice.

Mice

hCYP2D6

Strain Name：C57BL/6Smoc-Cyp2dtm(hCYP2D6)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-215024

The endogenous mouse Cyp2d22 gene was replaced by human CYP2D6 gene.

Mice

hTIGIT(3)

Strain Name：C57BL/6Smoc-Tigittm3(hTIGIT)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200244
Validation Data：Presence

The endogenous mouse Tigit gene was replaced by human TIGIT gene. While hTIGIT(Stock No.NM-HU-00053) mice function similarly to hTIGIT（3） mice ,for more detailed information please contact our technical advisor.

Mice

Cd200-KO

Strain Name：C57BL/6Smoc-Cd200em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190029

This Cd200 knockout mouse model was generated by knocking out the exon 2 region of the Cd200 .

Mice

hIL11RA

Strain Name：C57BL/6Smoc-Il11ra1tm1(hIL11RA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-204982

The endogenous mice Il11ra1 gene was replaced by human IL11RA gene.

Mice

hTNFRSF10B

Strain Name：C57BL/6Smoc-Tnfrsf10btm1(hTNFRSF10B)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210005

The endogenous mice Tnfrsf10B gene was replaced by human TNFRSF10B gene

Mice

Emx1-IRES-Cre

Strain Name：C57BL/6Smoc-emx1em1(IRES-Cre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200149
Validation Data：Presence

A IRES-Cre expression cassette was knocked into the Emx1 gene stop codon site.

Mice

hSIGLEC15(BALB/c)

Strain Name：BALB/cAnSmoc-Siglec15tm2(hSIGLEC15) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200001
Validation Data：Presence

The endogenous mouse Siglec15 gene was replaced by human SIGLEC15 gene .

Mice

IL1B-Luc-Tg

Strain Name：B6.Cg-Tg(IL1B-Luc)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-TG-00001
Validation Data：Presence  |  Publications：1piece

The transgenic mice model could be used to study transcriptional regulation of the IL-1βgene expression in the inflammatory process and evaluation the effect of anti-inflammatory drug in vivo.

Mice

hMASP2

Strain Name：C57BL/6Smoc-Masp2tm1(hMASP2)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000076
Validation Data：Presence

The endogenous mouse Masp2 gene was replaced by human MASP2 gene.

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