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Models

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Mice

Fah-KO(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1Fahem2Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-NSG-004

Exon 3 of Fah gene was deleted to generate Fah knockout mice.

Mice

NOD SCID

Strain Name：NOD.Cg-Prkdcscid/NifdcSmoc
Strain State：Repository Live | Cat. NO.：SM-019

The scid mutation has been transferred onto a diabetes-susceptible Non-Obese Diabetic (NOD) background. NOD-Scid mice do not develop diabetes, lack T and B cells, and are inherently immune deficient, making them good recipients for transplantation of human hematopoietic stem cells and human solid tumors. 

Mice

A2ml1-Flox

Strain Name：C57BL/6Smoc-A2ml1em1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of A2ml1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of A2ml1 gene.

Mice

hHGF(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1Hgfem1(hHGF)Smoc
Strain State：Developing | Cat. NO.：NM-NSG-013

The endogenous mouse Hgf gene was replaced by human HGF gene. (NMG Background)

Mice

C57BL/6

Strain Name：C57BL/6Smoc
Strain State：Repository Live | Cat. NO.：SM-001

C57BL/6 mice have a high reproductive capacity, a long life span, and a low tumor susceptibility. Male mice are aggressive and fight frequently. Diet can cause obesity, type II diabetes, and atherosclerosis in these mice. The C57BL/6 mouse is the first to have its entire genome sequenced. It is the most extensively used inbred mouse strain as a genetic basis for congenic and mutant mice. It is also used in genetics, metabolism, immunology, neurology, behavioral research, pharmacodynamics, and medication safety evaluation.

Mice

MHC Class II (I-A/I-E) -KO

Strain Name：C57BL/6Smoc-H2-Ab1em1H2-Aaem1 H2-Eb1em1H2-Eb2em1H2-Ea-ps em1 Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18032

All sequences from the upstream of mouse H2-Ab1 gene exon 2 to the upstream of the H2-Ea-ps gene exon 1 were knocked out to obtain H2-Ab1、H2-Aa、H2-Eb1、H2-Eb2、H2-Ea-ps knockout mouse models. These MHC class II molecule-deficient mice were on the C57BL/6J genetic background and also lacked cell surface expression of both class II-A and class II-E MHC proteins.

Mice

Cd4-IRES-DTRGFP

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Strain State： | Cat. NO.：

A IRES-DTREGFP expression cassette was knocked into the Cd4 gene stop codon site.

Mice

Trpv1-IRES-Cre

Strain Name：
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A Myc-IRES-Cre expression cassette was knocked into the Trpv1 gene stop codon site. Trpv1 is known as transient receptor potential cation channel, subfamily V, member 1. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying the pain caused by heat and capsaicin.

Mice

H2/H2-K1-KO(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1h2em2H2-K1em2Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-NSG-006

Exon 2 of H2;H2-K1 gene was deleted to generate H2;H2-K1 knockout mice.

Mice

hIL4-Tg(NMG)(2)

Strain Name：NOD-PrkdcscidIl2rgem2Tg(hIL4)Smoc
Strain State：Developing | Cat. NO.：NM-KI-220132

These transgenic mice carry humanized IL4.While hIL4-Tg(NMG)(Stock No.NM-KI-215004) mice function similarly to hIL4-Tg(NMG)(2) mice, for more detailed information please contact our technical advisor.

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