Therapeutic Target-Humanized Mice
Cre/Dre-Driver Mice
Immunodeficient NMG Mice
Strain Name:C57BL/6Smoc-Pdcd1tm1(hPDCD1)Tnfrsf4tm3(hTNFRSF4) Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00108
hPD-1(NM-HU-00015)was crossed with hOX40(NM-HU-00041)to generate hPD-1/hOX40.
Strain Name:C57BL/6Smoc-Hopxem1(2A-DreERT2)Smoc Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-190035 Validation Data:Presence | Publications:1piece
A 2A-DreERT2 expression cassette was knocked into the Hopx gene stop codon site.
Strain Name:C57BL/6Smoc-Akt2em1Smoc Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-190742
Exon 3-4 of Akt2 gene was deleted to generate Akt2 knockout mice.
Strain Name:C57BL/6Smoc-Vil1em(CreERT2)2Smoc Strain State:Repository Live | Cat. NO.:NM-KI-225020 Validation Data:Presence
CreERT2 expression cassette was knocked into the Vil1 gene .
Strain Name:C57BL/6Smoc-Il17ftm2(hIL17F)Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190007 Validation Data:Presence
The endogenous mouse Il17 gene was replaced by human IL17F gene.
Strain Name:BALB/cAnSmoc-Cd40lgtm1(hCD40L)Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000052
The endogenous mouse Cd40lg gene was replaced by human CD40L gene.
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-pA-Ins-Ins-TetO-Dre-IRES-BFP-pA-Ins-Ins)Smoc Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-190020
The SA-polyA-Ins-Ins-TetO-Dre-IRES-BFP-polyA-Ins-Ins cassette is inserted in mouse Rosa26 loci.
Strain Name:C57BL/6Smoc-H2-K1tm1(hHLA-A*1101)Smoc Strain State:Repository Live | Cat. NO.:NM-HU-204987 Validation Data:Presence
The endogenous mice H2-K1 gene was replaced by human HLA-A11.1 gene.
Strain Name:C57BL/6Smoc-Il4ratm1(hIL4R)Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190008 Validation Data:Presence
The endogenous mouse Il4ra gene was replaced by human IL4R gene.
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-dCas9-VPR-IRES-EGFP-WPRE-pA) Strain State:Repository Live | Cat. NO.:NM-KI-18004
These mice harbor a CAG-LSL-dCas9-VPR(VP64-p65-Rta)-eGFP-pA conditional expression cassette in mouse Rosa26 loci. This strain can be used in CRISPR mediated target gene transcriptional activation (CRISPRa).
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