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Mice

Rorc-2A-tdTomato-2A-DTR

Strain Name:C57BL/6Smoc-Rorcem(T2A-tdTomato-P2A-DTR)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-204991

T2A-tdTomato-P2A-DTR expression cassette was knocked into the Rorc gene .

Mice

R26-LSL-hIL15-Flag-IRES-EGFP

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem(CAG-Loxp-Stop-Loxp-Kozak-hIL2 signal peptide-hIL15-Flag-IRES-EGFP-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-220130

CAG-Loxp-Stop-Loxp-Kozak-hIL2 signal peptide-hIL15-Flag-IRES-EGFP-polyA expression cassette was knocked into the the Rosa26 locus

Mice

Zbtb46-IRES-Cre

Strain Name:C57BL/6Smoc-Zbtb46em1(IRES-iCre)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200096

A  IRES-iCre expression cassette was knocked into the Zbtb46 gene stop codon site. This strain carries a significant risk of reproductive system leakage. Avoid using homozygotes and female Cre mice. It is recommended to use male mice, as they have a lower probability of leakage. After mating, offspring should be genotyped and promptly checked for any occurrence of reproductive leakage.

Mice

hPD-L1/hCD27(2)

Strain Name:C57BL/6Smoc-Cd274em1(hPD-L1)Cd27tm3(hCD27)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200274

hPD-L1(NM-HU-00062) was crossed with hCD27(2)(NM-HU-190035)to generate hPD-L1/hCD27(2) mice.While hPD-L1/hCD27 (Stock No.NM-HU-18023) have been pulled from shelves for some reasons.

Mice

hPD-1/hCTLA-4

Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Ctla4em1(hCTLA4)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00079

hPD-1(NM-HU-00015) was crossed with hCTLA4(NM-HU-00014)to generate hPD-1/hCTLA4 mice

Mice

hCD33

Strain Name:C57BL/6Smoc-Cd33em3(CD33)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200002

The endogenous mouse Cd33 gene was replaced by human CD33 gene .

Mice

Ly6g-2A-CreERT2

Strain Name:C57BL/6Smoc-Ly6gem3(2A-CreERT2)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200218

A 2A-CreERT2 expression cassette was knocked into the Ly6g gene start codon site.

Mice

BALB/c Nude

Strain Name:BALB/cAnSmoc-Foxn1nu/Smoc
Strain State:Repository Live | Cat. NO.:SM-014

This strain carries a Foxn1nu mutation on the BALB/c background which will lead to T cell deletion. At the same time, the response to thymus-dependent antigens is limited, resulting in impaired B cell function while NK cells, macrophages, and antigen-presenting cells function normally. The complement activity is normal as well. Hair dysplasia causes aberrant hair growth in which the majority of the hair cannot protrude from the surface, resulting in a naked mouse phenotype.

Mice

Aire-KO

Strain Name:C57BL/6Smoc-Aireem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-2112347

Exon 8 of Aire gene was deleted to generate Aire knockout mice.

Mice

hCD3E/hSDC1

Strain Name:C57BL/6Smoc-Cd3eem1(hCD3E)Sdc1em1(hSDC1)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220021

hCD3E(NM-HU-00114) was crossed with hSDC1(NM-HU-2000026) to generate hCD3E/hSDC1 mice.

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