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Models

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Mice

Wls-Flox

Strain Name:B6;129S-Wlstm1(flox)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-CKO-00027

Mice homozygous for this conditional allele possess loxP sites flanking exon 3 of the targeted gene. When bred to mice that express Cre recombinase, the resulting offspring will have the exon encoding this gene deleted in the cre-expressing tissue(s).

Mice

hIL2/hIL2RA/hIL2RB/hIL2RG

Strain Name:C57BL/6Smoc-Il2tm3(hIL2)Il2ratm1(hIL2RA)Il2rgem1(IL2RG)Il2rbtm1(hIL2RB)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210415

hIL2/hIL2RA(NM-HU-200275) was crossed with hIL2RA/hIL2RB/hIL2RG(NM-HU-210414) to generate hIL2/hIL2RA/hIL2RB/hIL2RG mice.

Mice

Dppa3-IRES-Cre

Strain Name:C57BL/6Smoc-Dppa3em1(IRES-Cre)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-00040

The IRES-Cre cassette was inserted into 3'UTR of Dppa(Stella) gene which express during embryonic development.

Mice

hIL23A

Strain Name:C57BL/6Smoc-Il23aem3(hIL23A)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-18030

The endogenous mouse Il23a gene was replaced by humanIL23A gene .

Mice

Col2a1-2A-CreERT2

Strain Name:C57BL/6Smoc-Col2a1em1(2A-CreERT2)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-18029

A 2A-CreERT2 expression cassette was knocked into the stop codon of Col2a1 gene to establish a Col2a1-CreERT2 recombinase tool mouse.The strain cannot breed homozygotes, and it is recommended to use heterozygotes for research.

Mice

Isl1-CreERT2

Strain Name:C57BL/6Smoc-Isl1em1(CreERT2) Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-00013

CreERT2 was inserted at the start codon (ATG site). The KI mice have a tamoxifen-inducible cre-mediated recombination system.

Mice

Drd1-2A-CreERT2

Strain Name:C57BL/6Smoc-Drd1em1(2A-CreERT2-WPRE-pA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-18016

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Drd1 gene via homologous recombination to establish a tamoxifen inducible Drd1-CreERT2 tool stain. This strain can be used to knockout target gene in Drd1+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

Mice

Hopx-2A-DreERT2

Strain Name:C57BL/6Smoc-Hopxem1(2A-DreERT2)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-190035

A 2A-DreERT2 expression cassette was knocked into the Hopx gene stop codon site.

Mice

hCD3E(2)

Strain Name:C57BL/6Smoc-Cd3eem2(hCD3E)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210023

The endogenous mice Cd3e gene was replaced by human CD3E gene. While hCD3E(Stock No.NM-HU-00114) mice function similarly to hCD3E(2) mice,for more detailed information please contact our technical advisor.

Mice

Trp63-DreERT2

Strain Name:C57BL/6Smoc-Trp63em1(DreERT2-Wpre-polyA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-190029

A DreERT2-Wpre-polyA expression cassette was knocked into the exon4 of Trp63 gene.

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