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Models

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Mice

Nkx2-1-CreERT2

Strain Name:C57BL/6Smoc-Nkx2-1em1(CreERT2-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200123
Validation Data:Presence

A CreERT2-pA expression cassette was knocked into the Nkx2-1 gene start codon site. Nkx2-1, a key molecule in lung development, is expressed in adult bronchial and alveolar type Ⅱ epithelial cells. Besides, Nkx2-1 expression as a prognostic marker is also been applied to lung cancer research including lung adenocarcinoma.

Mice

hHLA-A2.22

Strain Name:C57BL/6Smoc-H2-D1tm1(hHLA-A2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-204988
Validation Data:Presence

The endogenous mice H2-D1 gene was replaced by human HLA-A2 gene.

Mice

hCRLF2

Strain Name:C57BL/6Smoc-Crlf2tm1(hCRLF2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210028
Validation Data:Presence

The endogenous mice Crlf2 gene was completely or partially replaced by human CRLF2 gene via ESC targeting.

Mice

Ifngr1/Ifnar1-KO

Strain Name:C57BL/6Smoc-Ifngr1em1Ifnar1em1Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-190425
Validation Data:Presence

This Ifngr1 and Ifnar1 double knockout strain is established by crossing Ifngr1-KO and Ifnar1-KO mice together.

Mice

a-IRES-Cre

Strain Name:C57BL/6Smoc-atm1(Cre)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200027
Publications:1piece

A IRES-Cre expression cassette was knocked into the a gene stop codon site via ESC targeting. Male mice with a germline Cre leak expression condition, please use female mice and flox mice for breeding crosses. References are available, please see the website for details.

Mice

hCD22

Strain Name:C57BL/6Smoc-Cd22tm2(hCD22)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000014
Validation Data:Presence

The endogenous mouse Cd22 gene was replaced by human CD22 gene.

Mice

hCD3E(2)

Strain Name:C57BL/6Smoc-Cd3etm2(hCD3E)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210023

The endogenous mice Cd3e gene was replaced by human CD3E gene. While hCD3E(Stock No.NM-HU-00114) mice function similarly to hCD3E(2) mice,for more detailed information please contact our technical advisor.

Mice

hCD47(Balb/c,2)

Strain Name:BALB/cAnSmoc-Cd47tm2(hCD47)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210359
Validation Data:Presence

The endogenous mice Cd47 gene was replaced by human CD47 gene. While hCD47(BALB/c)(Stock No.NM-HU-2000022) mice function similarly to hCD47(BALB/c,2) mice, for more detailed information please contact our technical advisor.

Mice

Cd19-IRES-EGFP-Luc

Strain Name:C57BL/6Smoc-Cd19em1(IRES-EGFP-Luci)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200058

A IRES-EGFP-Luci expression cassette was knocked into the Cd19 gene stop codon site.

Mice

hTIM3

Strain Name:C57BL/6Smoc-Havcr2tm1(hHAVCR2)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00054
Validation Data:Presence

The endogenous mouse Tim3 gene was replaced by human TIM3 gene .

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