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Models

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Mice

hEGFR

Strain Name：C57BL/6Smoc-Egfrtm1(hEGFR)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200227
Validation Data：Presence

The endogenous mice Egfr gene was replaced by human EGFR gene. While hEGFR(2)(Stock No.NM-HU-200232) mice have been pulled from shelves for some reasons.

Mice

hPD-1/hPD-L1

Strain Name：C57BL/6Smoc-Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00100
Validation Data：Presence

hPD-1(NM-HU-00015) was crossed with hPD-L1(NM-HU-00062)to generate hPD-1/hPD-L1 mice

Mice

Pten-Flox

Strain Name：C57BL/6Smoc-Ptenem1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-18004
Publications：1piece

These Pten flox mice possess loxP sites flanking exons 5 via CRISPR/Cas mediated recombination. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

hTLR7

Strain Name：C57BL/6Smoc-Tlr7tm1(hTLR7)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18027
Validation Data：Presence

The endogenous mouse Tlr7 gene was replaced by humanTLR7 gene.

Mice

C57BL/6

Strain Name：C57BL/6
Strain State：Repository Live | Cat. NO.：SM-001
Validation Data：Presence

It was the first mouse strain to have its genome sequenced. With black coat color, it is recognized as the "standard" inbred strain and provides genetic background for numerous mutant genes. It is characterized by stable strain properties, ease of breeding, uniform stress responses, and high precision in experimental results.

Mice

hCD27(2)/hFCGR2B

Strain Name：C57BL/6Smoc-Cd27tm3(hCD27)Fcgrt2btm2(hFCGRT2B)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210405

hCD27(2) (NM-HU-190035) was crossed with hFCGR2B (NM-HU-2000010) to generate hCD27(2)/hFCGR2B mice.

Mice

Abcd1-KO

Strain Name：C57BL/6Smoc-Abcd1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-2106014

Exon 2 of Abcd1 gene was deleted to generate Abcd1 knockout mice.

Mice

Cx3cr1-CreERT2

Strain Name：C57BL/6Smoc-Cx3cr1em1(creERT2-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200157
Validation Data：Presence

A creERT2-WPRE-polyA expression cassette was knocked into the Cx3cr1 gene start codon site.

Mice

hIL6R

Strain Name：C57BL/6Smoc-Il6ratm1(hIL6R)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00044

The endogenous mouse Il6ra gene was replaced by human IL-6R gene .

Mice

Shh-CreERT2

Strain Name：C57BL/6Smoc-Shhem1(CreERT2-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200145
Validation Data：Presence

A CreERT2-WPRE-polyA expression cassette was knocked into the Shh gene start codon site.

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