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Models

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Mice

hCD40/hCD40L

Strain Name：C57BL/6Smoc-CD40tm2(hCD40)Cd40lgtm1(hCD40L)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200268
Validation Data：Presence

hCD40（NM-HU-00076）was crossed with hCD40L（NM-HU-2000033）to generate hCD40/hCD40L mice

Mice

Glp1r-IRES-Cre

Strain Name：C57BL/6Smoc-Glp1rem1(IRES-iCre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200134
Validation Data：Presence

A IRES-iCre expression cassette was knocked into the Glp1r gene stop codon site.

Mice

Ucp1-CreERT2

Strain Name：C57BL/6Smoc-Ucp1em1(Kozak-CreERT2-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190102
Validation Data：Presence

A Kozak-CreERT2-WPRE-polyA expression cassette was knocked into the Ucp1 gene start codon site.

Mice

A2m-KO

Strain Name：C57BL/6Smoc-A2mem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190549

Exon 4 of A2m gene was deleted to generate A2m knockout mice.

Mice

hPD-L1/hCD28

Strain Name：C57BL/6Smoc-Cd274tm1(hPD-L1)Cd28tm2(hCD28)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210019

hPD-L1(NM-HU-00062) was crossed with hCD28(NM-HU-190011) to generate hPD-L1/hCD28 mice

Mice

hAR

Strain Name：C57BL/6Smoc-Artm2(hAR)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225061
Validation Data：Presence

The endogenous mouse Ar gene was replaced by human AR gene.

Mice

hCD19/hCD3E

Strain Name：C57BL/6Smoc-Cd19tm1(hCD19)Cd3etm1(hCD3E)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190027
Validation Data：Presence

This CD19 and CD3E double knockin strain is established by crossing CD19-HU and CD3E-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

hANGPTL3(3)

Strain Name：C57BL/6Smoc-Angptl3tm2(hANGPTL3)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-210037
Validation Data：Presence

The endogenous mice Angptl3 gene was replaced by human ANGPTL3 gene. While hANGPTL3(Stock No.NM-HU-200113) have been pulled from shelves for some reasons and hANGPTL3(4)(Stock No.NM-HU-210036) mice function similarly to hANGPTL3(3) mice, for more detailed information please contact our technical advisor.

Mice

hLAG3

Strain Name：B6.129S-Lag3tm1(hLAG3)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00049
Validation Data：Presence

The endogenous mouse Lag3 gene exon1-7 was replaced by human LAG3 gene extracellular region by homologous recombination.

Mice

hIL9

Strain Name：C57BL/6Smoc-Il9tm3(hIL9)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-18029
Validation Data：Presence

The endogenous mouse Il9 gene was replaced by human IL9 gene .

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