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Models

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Mice

Tmem119-2A-CreERT2

Strain Name：C57BL/6Smoc-Tmem119em2(P2A-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200234
Validation Data：Presence  |  Publications：2piece

A P2A-CreERT2 expression cassette was knocked into the Tmem119 gene stop codon site.

Mice

Ccr2-IRES-DTRGFP

Strain Name：C57BL/6Smoc-Ccr2em1(IRES-DTRGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-210102
Validation Data：Presence

IRES-DTRGFP expression cassette was knocked into the Ccr2 gene .

Mice

HLA-A2.22/B2M

Strain Name：C57BL/6Smoc-H2-D1tm1(hB2M/HLA-A2)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-210010

The endogenous mice H2-D1 gene was replaced by human B2M/HLA-A2 gene

Mice

NVG-hIL15

Strain Name：NOD-PrkdcscidIl2rgem1Il15(hIL15)Smoc
Strain State：Repository Live | Cat. NO.：GM-NVG-210001
Validation Data：Presence

The endogenous mice Il15 gene was replaced by human IL15 gene.

Mice

hCD27(2)

Strain Name：C57BL/6Smoc-Cd27tm3(hCD27)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190035
Validation Data：Presence

The endogenous mouse Cd27 gene was replaced by human CD27 gene. While hCD27 mice(Stock No.NM-HU-00093）have been pulled from shelves for some reasons.

Mice

Ar-Flox

Strain Name：B6;129S-Artm1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-00110
Publications：2piece

These mice carry loxP sites flanking exon 2 of Ar gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Ar gene.

Mice

Aqp5-2A-CreERT2

Strain Name：C57BL/6Smoc-Aqp5em1(2A-CreERT2-Wpre-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200313
Validation Data：Presence

2A-CreERT2-Wpre-pA expression cassette was knocked into the Aqp5 gene stop codon site.

Mice

NOD SCID

Strain Name：NOD.Cg-Prkdcscid/NifdcSmoc
Strain State：Repository Live | Cat. NO.：SM-019
Validation Data：Presence

The strain was developed on background of non-obese diabetic (NOD) mouse with spontaneous scid mutation. NOD SCID mouse, insusceptible to diabetes, possesses reduced activity of T cells and B cells, and defect in innate immunity.NOD SCID mouse is compatible with a wider range of engraftment of cell lines in comparison with nude mouse; And it is broadly applied to construction of PDX models. However, due to a short life span(8-9 months) caused by lethal thymic lymphomas, it is unsuitable for long-term in vivo assays.

Mice

Pdx1-2A-CreERT2

Strain Name：C57BL/6Smoc-Pdx1em1(Avi tag-2A-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18042
Validation Data：Presence

An Avi tag-2A-CreERT2 cassette was inserted at the Pdx1 gene stop codon site .

Mice

Apc-Flox

Strain Name：C57BL/6Smoc-Apctm2(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-200013

These mice carry loxP sites flanking exon 15 of Apc gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Apc gene.

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