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Models

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Mice

Axin2-CreERT2

Strain Name：C57BL/6Smoc-Axin2em1(CreERT2-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200109
Validation Data：Presence

A CreERT2-pA expression cassette was knocked into the Axin2 gene start codon site. As Axin2 is an intracellular protein, it is essential for identifying a surface marker for stem cell purification. When these Axin2-CreERT2 mice are bred with mice containing a loxP-flanked sequence of interest, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the flanked sequences in Axin2 expressing cells.

Mice

hPD-1/hPD-L1/hOX40

Strain Name：C57BL/6Smoc-Tnfrsf4tm3(hTNFRSF4)Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00122

hPD-1(NM-HU-00015),hPD-L1(NM-HU-00062) were crossed with hOX40(NM-HU-00041) to generate hPD-1/hPD-L1/hOX40.

Mice

BALB/c Nude

Strain Name：BALB/c Nude
Strain State：Repository Live | Cat. NO.：SM-014
Validation Data：Presence

BALB/c Nude

Mice

hCTLA-4

Strain Name：C57BL/6Smoc-Ctla4tm1(hCTLA4) Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00014
Validation Data：Presence

The endogenous mouse Ctal4 gene was replaced by human CTLA4 gene. While hCTLA4(2)(Stock No.NM-HU-190038) mice function similarly to hCTLA4 mice,for more detailed information please contact our technical advisor.

Mice

hCD24

Strain Name：C57BL/6Smoc-Cd24atm1(hCD24)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000060
Validation Data：Presence

The endogenous mouse Cd24a gene was replaced by human CD24 gene. While hCD24(2)(Stock No.NM-HU-215025) mice function similarly to hCD24 mice, for more detailed information please contact our technical advisor.

Mice

R26-CAG-LSL-tdTomato-2A-DTR

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem(CAG-LSL-R-tdTomato-2A-DTR)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-210094
Validation Data：Presence

These mice harbor a CAG-LSL-R-tdTomato-2A-DTR cassette in the Rosa26 locus generated by homologous recombination.

Mice

hCCR8(BALB/c)

Strain Name：BALB/cAnSmoc-Ccr8tm1(hCCR8)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000048
Validation Data：Presence

The endogenous mouse Ccr8 gene was replaced by human CCR8 gene.

Mice

Abcg2-KO

Strain Name：C57BL/6Smoc-Abcg2em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18013
Validation Data：Presence

Exon3-5 of Abcg2 gene were deleted to generate Abcg2 knockout mice.

Mice

hTTR

Strain Name：C57BL/6Smoc-Ttrtm1(hTTR)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225087
Validation Data：Presence

The endogenous mouse Ttr gene was replaced by human TTR gene.

Mice

hB7H4

Strain Name：C57BL/6Smoc-Vtcn1tm1(hVTCN1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190004

This VTCN1 humanized mouse model was established by replacing the mouse Vtcn1 gene with the human VTCN1. While hB7H4(2)(Stock No.NM-HU-190075) mice function similarly to hB7H4 mice,for more detailed information please contact our technical advisor.

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