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Models

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Mice

Pdyn-IRES-Cre

Strain Name：C57BL/6Smoc-Pdynem1(IRES-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200089
Validation Data：Presence

A IRES-iCre expression cassette was knocked into the Pdyn gene stop codon site. Pdyn encodes prodynorphin. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying depression, stress, anxiety, pain response, circadian rhythm and appetite control.

Mice

Gpr12-KO

Strain Name：C57BL/6Smoc-Gpr12em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200978
Validation Data：Absence

Exon 2 of Gpr12 gene was deleted to generate Gpr12 knockout mice.

Mice

KPC(2)

Strain Name：C57BL/6Smoc-Trp53tm7(R270H-flox)Krasem4(LSL-G12D)Tg(Pdx1-cre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-220014
Validation Data：Absence

Trp53-LSL-R270H, Kras-LSL-G12D were crossed with Pdx1-Cre-Tg to generate KPC mice. While KPC mice function similarly to KPC(2) mice, for more detailed information please contact our technical advisor.

Mice

Taar1-KO

Strain Name：C57BL/6Smoc-Taar1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-2112327
Validation Data：Absence

Exon 1 of Taar1 gene was deleted to generate Taar1 knockout mice.

Mice

hIL2/hIL2RA

Strain Name：C57BL/6Smoc-Il2tm3(hIL2)Il2ratm1(hIL2RA)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200275
Validation Data：Presence

hIL2(NM-HU-190048) was crossed with hIL2R(NM-HU-190064) to generate IhIL2/hIL2RA mice.

Mice

Pnpla3-I148M

Strain Name：C57BL/6Smoc-Pnpla3em1(I148M)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200185
Validation Data：Absence

These mice carry a I148M mutation of Pnpla3 gene.

Mice

Clec4f-2A-CreERT2

Strain Name：C57BL/6Smoc-Clec4fem(2A-CreERT2)1Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-225083
Validation Data：Absence

2A-CreERT2 expression cassette was knocked into the Clec4f gene .

Mice

Il23a-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il23aem1(Luc-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00057
Validation Data：Absence

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il23a.

Mice

Xirp1-KO

Strain Name：C57BL/6Smoc-Xirp1em1Smoc
Strain State：Developing | Cat. NO.：TBD
Validation Data：Absence

Exon 2 of Xirp1 gene was deleted to generate Xirp1 knockout mice.

Mice

Karma-2A-tdTomato-2A-DTR

Strain Name：C57BL/6Smoc-Gpr141bem1(2A-tdTomato-2A-DTR)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-210116
Validation Data：Absence

2A-tdTomato-2A-DTR expression cassette was knocked into the Karma gene.

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