Therapeutic Target-Humanized Mice
Cre/Dre-Driver Mice
Immunodeficient NMG Mice
Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Sirpaem2(hSIRPA)Smoc Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000089 Validation Data：Absence
hPD-1(NM-HU-00015) was crossed with hSIRPA(2) (NM-HU-18015) to generate hPD-1/hSIRPA(2).
Strain Name：C57BL/6Smoc-Notch3em1(R170C)Smoc Strain State：Repository Live | Cat. NO.：NM-KI-200254 Validation Data：Absence
These mice carry a p.R170C mutation of Notch3 gene.
Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-NFE2L2(G81S)-IRES-Luciferase-2A-tdTomato)Smoc Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190077 Validation Data：Absence
These mice harbor a CAG-LSL-NFE2L2(G81S)-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.
Strain Name：C57BL/6Smoc-Arhgef10em1Smoc Strain State：Developing | Cat. NO.：TBD Validation Data：Absence
Exon 5 of Arhgef10 gene was deleted to generate Arhgef10 knockout mice.
Strain Name：C57BL/6Smoc-Sox2em1(CreERT2-polyA)Smoc Strain State：Repository Live | Cat. NO.：NM-KI-200084 Validation Data：Presence
The coding region of Sox2 gene was replaced by a CreERT2-polyA expression cassette.
Strain Name：C57BL/6Smoc-Rag1em1Smoc Strain State：Repository Live | Cat. NO.：NM-KO-252600 Validation Data：Absence
The exon 2 of Rag1 gene was deleted to generate Rag1 knockout mouse.
Strain Name：C57BL/6Smoc-Spnem1(hSPN)Smoc Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225032 Validation Data：Presence
The endogenous mouse Spn gene was replaced by human SPN gene.
Strain Name：C57BL/6Smoc-Trpm2em1(T2A-iCre)Smoc Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200097 Validation Data：Absence
A T2A-iCre expression cassette was knocked into the Trpm2 gene stop codon site.
Strain Name：C57BL/6Smoc-Neflem1(N98S)Smoc Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200251 Validation Data：Absence
These mice carry a p.N98S mutation of Nefl gene.
Strain Name：C57BL/6Smoc-Cx3cr1em1(P2A-EGFP)Smoc Strain State：Repository Live | Cat. NO.：NM-KI-210099 Validation Data：Presence
P2A-EGFP expression cassette was knocked into the Cx3cr1 gene via CRISPR/Cas9 mediated recombination.
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