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Models

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Mice

Stat3-Flox(in-frame mutation)

Strain Name:C57BL/6Smoc-Stat3em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-200225

These mice carry loxP sites flanking exon 18-20 of Stat3 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Stat3 gene. The experimental strategy was designed with reference to the following publications: (PMID: 14566054; 17660847; 12571365). While Stat3-Flox(Stock No.NM-CKO-200050)mice carrying the loxP sites flanking exon 12-14 of Stat3 gene.

Mice

hCD3EDG/hPD-L1

Strain Name:C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cd274tm1(hPD-L1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220112

hCD3EDG(NM-HU-220120) mice were crossed with hPD-L1(NM-HU-00062) mice to generate hCD3EDG/hPD-L1 mice

Mice

Ltf-Cre-IRES-tdTomato

Strain Name:C57BL/6Smoc-Ltfem1(iCre-IRES-tdTomato-WPRE-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200116
Validation Data:Presence

A iCre-IRES-tdTomato-WPRE-pA expression cassette was knocked into the Ltf gene start codon site.

Mice

Aadacl2fm2-Flox

Strain Name:C57BL/6Smoc-Aadacl2fm2em1(flox)Smoc
Strain State:Developing | Cat. NO.:NM-CKO-253920

These mice carry loxP sites flanking exon 2 of Aadacl2fm2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aadacl2fm2 gene.

Mice

hSIRPA(2)/hCD47/hPD-L1

Strain Name:C57BL/6Smoc-Sirpatm2(hSIRPA)Cd274tm1(hCD274)Cd47tm1(hCD47)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000095

hPD-L1(NM-HU-00062),hCD47(NM-HU-00050) was crossed with hSIRPA(2) (NM-HU-18015) to generate hSIRPA(2)/hCD47/hPD-L1.

Mice

Kank1-2A-DreERT2

Strain Name:C57BL/6Smoc-Kank1em1(2A-DreERT2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-190040
Validation Data:Presence  |  Publications:1piece

A 2A-DreERT2 expression cassette was knocked into the Kank1 gene stop codon site.

Mice

R26-LNL-PB

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LNL-PB-V5)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-00065

These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven piggyBac transposase. The targeted mutation was inserted into the Gt(ROSA)26Sor locus by homologous recombination. PiggyBac transposase is expressed when bred to mice that express Cre recombinase.

Mice

Zfp36-KO

Strain Name:C57BL/6Smoc-Zfp36em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-2112247

exon 2 of Zfp36 gene was deleted to generate Zfp36 knockout mice.

Mice

Il33-KO(3)

Strain Name:C57BL/6Smoc-Il33em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-210206

Il33-KO(3) mice(Stock No.NM-KO-210206) carry a knockout allele derived from the targeted deletion of exon 2. While Il33-KO mice(Stock No.NM-KO-00099) have been pulled from shelves for some reasons and Il33-KO(2) mice(Stock No.NM-KO-190436) carrying the exon 3-7 deletion.

Mice

hLAIR1/hPD-1/hPD-L1

Strain Name:C57BL/6Smoc-Lair1tm2(LAIR1)Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220040

hLAIR1(NM-HU-2000011),hPD-1(NM-HU-00015) and hPD-L1(NM-HU-00062) were crossed tegother to generate hLAIR1/hPD-1/hPD-L1 mouse.

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