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Models

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Mice

hTIGIT/hTNFR2

Strain Name:C57BL/6Smoc-Tigittm3(hTIGIT)Tnfrsf1btm2(hTNFRSF1B)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210371

hTIGIT(3)(NM-HU-200244) was crossed with hTNFRSF1B(NM-HU-190010)to generate hTIGIT(3)/hTNFRSF1B mice

Mice

CD8a-IRES-Luc-2A-tdTomato(BALB/c)

Strain Name:BALB/cAnSmoc-CD8aem5(IRES-Akaluc-2A-tdTomato)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200208
Validation Data:Presence

A IRES-luci-2A-tdTomato expression cassette was knocked into the CD8a gene stop codon site.

Mice

Cd68-2A-Cre

Strain Name:C57BL/6Smoc-Cd68em5(2A-Cre-WPRE-polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200192
Validation Data:Presence

This Cd68-Cre tool mouse model was established by inserting a 2A-Cre-WPRE-polyA co-expression cassette into the stop codon of Cd68 gene .

Mice

hCD33

Strain Name:C57BL/6Smoc-Cd33tm3(CD33)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200002
Validation Data:Presence

The endogenous mouse Cd33 gene was replaced by human CD33 gene .

Mice

hCD28/hCD38(2)

Strain Name:C57BL/6Smoc-Cd28tm2(hCD28)Cd38tm2(CD38)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210350

hCD38(NM-HU-190059) was crossed with hCD28(NM-HU-190011) to generate hCD28/hCD38 mice.

Mice

hIL23A

Strain Name:C57BL/6Smoc-Il23atm3(hIL23A)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-18030
Validation Data:Presence

The endogenous mouse Il23a gene was replaced by humanIL23A gene .

Mice

A2ml1-Flox

Strain Name:C57BL/6Smoc-A2ml1em1(flox)Smoc
Strain State:Developing | Cat. NO.:NM-CKO-253735

These mice carry loxP sites flanking exon 8-11 of A2ml1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of A2ml1 gene.

Mice

F8-KO

Strain Name:B6.129S-F8tm1Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-00012
Validation Data:Presence

F8-KO mice (Stock No.NM-KO-00012)carry a knockout allele derived from the targeted deletion of exon 16-19. While F8-KO(2) mice (Stock No.NM-KO-200608) carrying the exon 1-26 deletion.

Mice

Tmem119-2A-DTRGFP

Strain Name:C57BL/6Smoc-Tmem119em4(P2A-DTRGFP)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200235

A P2A-DTRGFP expression cassette was knocked into the Tmem119 gene stop codon site.

Mice

hFCGR2B

Strain Name:C57BL/6Smoc-Fcgr2btm3(hFCGR2B)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000010
Validation Data:Presence

The endogenous mouse Fcgr2b gene was replaced by human FCGR2B gene.

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