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Models

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Mice

C9orf72-KO

Strain Name：C57BL/6JSmo-C9orf72em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-201246

Exon 4-5 of C9orf72 gene was deleted to generate C9orf72 knockout mice.

Mice

Ar-Flox

Strain Name：B6;129S-Artm1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-00110
Publications：2piece

These mice carry loxP sites flanking exon 2 of Ar gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Ar gene.

Mice

hHGF

Strain Name：C57BL/6JSmo-Hgftm1(hHGF)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200235

The endogenous mice Hgf gene was replaced by human HGF gene.

Mice

CAG-Dre-Tg

Strain Name：C57BL/6JSmo-Tg(CAG-Dre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-TG-00026

These transgenic mice carry Dre recombinase driven by CAG promoter.

Mice

G6pc-Flox

Strain Name：C57BL/6JSmo-G6pcem1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200053

These mice carry loxP sites flanking exon 3 of G6pc gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of G6pc gene.

Mice

hMERTK

Strain Name：C57BL/6JSmo-Mertktm1(hMERTK)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000031
Validation Data：Presence

The endogenous mouse Mertk gene was replaced by human MERTK gene.

Mice

NOD SCID

Strain Name：NOD.Cg-Prkdcscid/NifdcSmoc
Strain State：Repository Live | Cat. NO.：SM-019
Validation Data：Presence

The strain was developed on background of non-obese diabetic (NOD) mouse with spontaneous scid mutation. NOD SCID mouse, insusceptible to diabetes, possesses reduced activity of T cells and B cells, and defect in innate immunity.NOD SCID mouse is compatible with a wider range of engraftment of cell lines in comparison with nude mouse; And it is broadly applied to construction of PDX models. However, due to a short life span(8-9 months) caused by lethal thymic lymphomas, it is unsuitable for long-term in vivo assays.

Mice

hCSF2RB

Strain Name：C57BL/6JSmo-Csf2rbtm1(hCSF2RB)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-225078
Validation Data：Presence

The endogenous mouse Csf2rb gene was replaced by human CSF2RB gene.

Mice

hIL9

Strain Name：C57BL/6JSmo-Il9tm3(hIL9)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-18029
Validation Data：Presence

The endogenous mouse Il9 gene was replaced by human IL9 gene .

Mice

R26-CAG-LSL-hTM6SF2*E167K-EGFP

Strain Name：C57BL/6JSmo-Gt(ROSA)26Sortm1(SA-Frt-2xpolyA-CAG-Frt-LSL-TM6SF2-IRES-GFP-WPRE-PA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200017

These mice harbor a SA-Frt-2xpolyA-CAG-Frt-LSL-TM6SF2-IRES-GFP-WPRE-PA cassette in the Rosa26 locus generated by homologous recombination.

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