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Models

About 230 results
Mice

H19-KO

Strain Name：C57BL/6Smoc-H19em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18045

The 3.8 kb region of the -4.6 kb to -0.8 kb upstream of the transcription start site was knocked out to obtain a H19 lncRNA gene mutant mouse strain.

Mice

Ergic1-KO

Strain Name：C57BL/6Smoc-Ergic1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200188

Exon 2 of Ergic1 gene was deleted to generate Ergic1 knockout mice.

Mice

Itgb3-KO

Strain Name：C57BL/6Smoc-Itgb3em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200270

Exon 2 of Itgb3 gene was deleted to generate Itgb3 knockout mice.

Mice

Slc4a7-KO

Strain Name：C57BL/6Smoc-Slc4a7em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200499

Exon 2 of Slc4a7 gene was deleted to generate Slc4a7 knockout mice.

Mice

Il13ra1-KO

Strain Name：C57BL/6Smoc-Il13ra1em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190457

Exon 2 of Il13ra1 gene was deleted to generate Il13ra1 knockout mice.

Mice

Nhlh2-KO

Strain Name：C57BL/6Smoc-Nhlh2em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190713

Exon 3 of Nhlh2 gene was deleted to generate Nhlh2 knockout mice.

Mice

Cckbr-KO

Strain Name：C57BL/6Smoc-Cckbrem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190609

Exon 3 of Cckbr gene was deleted to generate Cckbr knockout mice.

Mice

Cr2-Flox

Strain Name：C57BL/6Smoc-Cr2em1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200331

These mice carry loxP sites flanking exon 7-9 of Cr2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Cr2 gene.

Mice

CAG-LSL-dCas9-SPH-Tg

Strain Name：C57BL/6Smoc-Tg(CAG-LSL-dCas9-SPH)Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-00025

Cre-dependent SunTag-p65-HSF1 (SPH) transgenic mice were generated with piggyBac transposon system in F1 zygotes and crossed with wild type C57BL/6 mice., SPH transgenic mouse containing HA-tagged dCas9 fused with 10xGCN4, which is linked with p65-HSF1 and EGFP in tandem via P2A and T2A respectively. The transgene is driven by the ubiquitous CAG promoter and interrupted by a loxP-stop-loxP (LSL) cassette to render Cas9 expression inducible by the Cre recombinase. Expression of dCas9 can be detected using primary antibody: rabbit monoclonal antibody to HA-tag (1:1000, #3724, CST45) and secondary antibody: goat anti-rabbit Alexa Fluor 488 (1:1000, #A-11034, Thermo Fisher).

Mice

Vcan-KO

Strain Name：C57BL/6Smoc-Vcanem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190564

Exon 2 of Vcan gene was deleted to generate Vcan knockout mice.

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