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Models

About 230 results
Mice

C1qtnf6-KO

Strain Name：C57BL/6Smoc-C1qtnf6em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200071

Exon 2 of C1qtnf6 gene was deleted to generate C1qtnf6 knockout mice.

Mice

Padi4-KO

Strain Name：C57BL/6Smoc-Padi4em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190334

This Padi4 knockout mouse model was generated by knocking out the exon 3 region of the Padi4.

Mice

Serpinf1-KO

Strain Name：C57BL/6Smoc-Serpinf1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-233292

The exon 2-8 of Serpinf1 gene was deleted to generate Serpinf1 knockout mouse.

Mice

Mt1-Flox/Mt2-Flox

Strain Name：C57BL/6Smoc-Mt1 em1（flox）Mt2 em1（flox）Smoc
Strain State：Developing | Cat. NO.：NM-CKO-252576

The MT1-FLOX model was constructed based on Mt2-Flox (NM-CKO-226357) by inserting loxP sites on both sides of exon 2-3 of the Mt1 gene respectively. This flox mouse can be mated with tissue-specific Cre tool mice to obtain mouse models with the Mt1 gene knocked out in specific cell types or tissues.

Mice

Rag1-KO(Rag1-EGFP)

Strain Name：B6;129S-Rag1tm1(loxP-EGFP-PolyA-loxP-Neo-loxP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00069

A loxP-EGFP-PolyA-loxP-Neo-loxP expression cassette was knocked into the Rag1 gene start codon site. As a Rag1 knockout mouse model, this stain can be used in subcutaneous inoculation of liver cancer tissues and tumor cells. Tumors can esaily form and grow. The amount of T and B lymphocytes in peripheral blood of mice was extremely low tested by FACS, which was comparable to or lower than that of Nude mice, and there was a significant difference compared with wild type mice. The pathological sections of HE staining of tumor tissues showed that the tumor sections of Rag1 KO mice and Nude mice were similar. This strain has the potential to replace Nude, NOD-SCID mice as a tumor-bearing mouse model.

Mice

Foxp3-IRES-tdTomato-2A-Cre

Strain Name：C57BL/6Smoc-Foxp3em3(IRES-tdTomato-2A-iCre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190119

A IRES-tdTomato-2A-Cre expression cassette was knocked into the Foxp3 gene stop codon site. This strain is useful in studying regulatory T cell in autoimmunity, especially in type 1 diabetes.

Mice

Atxn2-KO

Strain Name：C57BL/6Smoc-Atxn2em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190920

Exon 6 of Atxn2 gene was deleted to generate Atxn2 knockout mice.

Mice

Vegfa-KO

Strain Name：C57BL/6Smoc-Vegfaem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190539

Exon 1-6 of Vegfa gene was deleted to generate Vegfa knockout mice.

Mice

Col3a1-KO

Strain Name：C57BL/6Smoc-Col3a1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-201256

Exon 2 of Col3a1 gene was deleted to generate Col3a1 knockout mice.

Mice

Ppib-KO

Strain Name：C57BL/6Smoc-Ppibem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-201195

Exon 2-3 of Ppib gene was deleted to generate Ppib knockout mice.

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