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Models

About 230 results
Mice

Rag2-KO(Rag2-EGFP)

Strain Name：B6;129S-Rag2tm1(loxP-EGFP-PolyA-loxP-Neo-loxP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00070

A loxP-EGFP-PolyA-loxP-Neo-loxP expression cassette was knocked into the Rag2 gene start codon site. As a Rag2 knockout mouse model, this stain can be used in subcutaneous inoculation of liver cancer tissues and tumor cells. Tumors can esaily form and grow. The amount of T and B lymphocytes in peripheral blood of mice was extremely low tested by FACS, which was comparable to or lower than that of Nude mice, and there was a significant difference compared with wild type mice. The pathological sections of HE staining of tumor tissues showed that the tumor sections of Rag2 KO mice and Nude mice were similar. This strain has the potential to replace Nude, NOD-SCID mice as a tumor-bearing mouse model.

Mice

Tbx21-KO

Strain Name：C57BL/6Smoc-Tbx21em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190157

This Tbx21 knockout mouse model was generated by knocking out the exon 2 region of the Tbx21.

Mice

C57BL/6

Strain Name：C57BL/6Smoc
Strain State：Repository Live | Cat. NO.：SM-001

C57BL/6 mice have a high reproductive capacity, a long life span, and a low tumor susceptibility. Male mice are aggressive and fight frequently. Diet can cause obesity, type II diabetes, and atherosclerosis in these mice. The C57BL/6 mouse is the first to have its entire genome sequenced. It is the most extensively used inbred mouse strain as a genetic basis for congenic and mutant mice. It is also used in genetics, metabolism, immunology, neurology, behavioral research, pharmacodynamics, and medication safety evaluation.

Mice

Lepr-KO

Strain Name：C57BL/6Smoc-Leprem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190663

Exon 5 of Lepr gene was deleted to generate Lepr knockout mice.

Mice

Cdkal1-Flox

Strain Name：C57BL/6Smoc-Cdkal1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-234794

These strains carry loxP sites flanking exon 5 of Cdkal1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Cdkal1 gene.

Mice

Irs1-KO

Strain Name：C57BL/6Smoc-Irs1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190827

Exon 1 of Irs1 gene was deleted to generate Irs1 knockout mice.

Mice

Hmga1-KO

Strain Name：C57BL/6Smoc-Hmga1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-2114155

Exon 3-5 of Hmga1 gene was deleted to generate Hmga1 knockout mice.

Mice

Cyb5r4-KO

Strain Name：C57BL/6Smoc-Cyb5r4em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200941

Exon 3 of Cyb5r4 gene was deleted to generate Cyb5r4 knockout mice.

Mice

Mafa-KO

Strain Name：C57BL/6Smoc-Mafaem1Smoc
Strain State：Developing | Cat. NO.：TBD

Exon 1 of Mafa gene was deleted to generate Mafa knockout mice.

Mice

Phox2a-KO

Strain Name：C57BL/6Smoc-Phox2aem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-201323

Exon 2 of Phox2a gene was deleted to generate Phox2a knockout mice.

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