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Models

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Mice

Mafa-KO

Strain Name：C57BL/6Smoc-Mafaem1Smoc
Strain State：Developing | Cat. NO.：NM-KO-260203

The exon 1 of Mafa gene was deleted to generate Mafa knockout mouse.

Mice

Rag2-KO(Rag2-EGFP)

Strain Name：B6;129S-Rag2tm1(loxP-EGFP-PolyA-loxP-Neo-loxP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00070
Validation Data：Presence

A loxP-EGFP-PolyA-loxP-Neo-loxP expression cassette was knocked into the Rag2 gene start codon site. As a Rag2 knockout mouse model, this stain can be used in subcutaneous inoculation of liver cancer tissues and tumor cells. Tumors can esaily form and grow. The amount of T and B lymphocytes in peripheral blood of mice was extremely low tested by FACS, which was comparable to or lower than that of Nude mice, and there was a significant difference compared with wild type mice. The pathological sections of HE staining of tumor tissues showed that the tumor sections of Rag2 KO mice and Nude mice were similar. This strain has the potential to replace Nude, NOD-SCID mice as a tumor-bearing mouse model.

Mice

Tbx21-KO

Strain Name：C57BL/6Smoc-Tbx21em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190157

This Tbx21 knockout mouse model was generated by knocking out the exon 2 region of the Tbx21.

Mice

Lepr-KO

Strain Name：C57BL/6Smoc-Leprem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190663

Exon 5 of Lepr gene was deleted to generate Lepr knockout mice.

Mice

Cdkal1-Flox

Strain Name：C57BL/6Smoc-Cdkal1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-234794

These strains carry loxP sites flanking exon 5 of Cdkal1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Cdkal1 gene.

Mice

Hmga1-KO

Strain Name：C57BL/6Smoc-Hmga1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-2114155

Exon 3-5 of Hmga1 gene was deleted to generate Hmga1 knockout mice.

Mice

Irs1-KO

Strain Name：C57BL/6Smoc-Irs1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190827

Exon 1 of Irs1 gene was deleted to generate Irs1 knockout mice.

Mice

Cyb5r4-KO

Strain Name：C57BL/6Smoc-Cyb5r4em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200941

Exon 3 of Cyb5r4 gene was deleted to generate Cyb5r4 knockout mice.

Mice

Gadd45gip1-Flox

Strain Name：C57BL/6Smoc-Gadd45gip1em1(flox)Smoc
Strain State：Developing | Cat. NO.：NM-CKO-253850

These mice carry loxP sites flanking exon 1 of Gadd45gip1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Gadd45gip1 gene.

Mice

Phox2a-KO

Strain Name：C57BL/6Smoc-Phox2aem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-201323

Exon 2 of Phox2a gene was deleted to generate Phox2a knockout mice.

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