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Models

About 197 results
Mice

Prrx1-KO

Strain Name：C57BL/6Smoc-Prrx1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00165

Exon1 of Prrx1 gene was targeted to generate Prrx1 knockout mice.

Mice

Atg5-KO

Strain Name：C57BL/6Smoc-Atg5em2Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18004

Exon3 of Atg5 gene was targeted and a additional 58bp sequence insertion caused a frameshift mutation.

Mice

Trpv6-KO

Strain Name：B6;129S-Trpv6tm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00168

Exon2 of Trpv6 gene was targeted to generate Trpv6 knockout mice.

Mice

Tnf-KO

Strain Name：C57BL/6Smoc-Tnfem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-00100
Validation Data：Presence

Exon2-3 of Tnf gene were targeted to generate the Tnf knockout mice.

Mice

Clec3b-KO

Strain Name：B6;129S-Clec3btm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00169

Exon1-2 of Clec3b gene were targeted to generate Clec3b knockout mice.

Mice

Il1f6-KO

Strain Name：C57BL/6Smoc-Il1f6em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00097

Exon2-3 of Il1f6 gene were targeted to generate Il1f6 knockout mice.

Mice

Wls-Flox

Strain Name：B6;129S-Wlstm1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-00027

Mice homozygous for this conditional allele possess loxP sites flanking exon 3 of the targeted gene. When bred to mice that express Cre recombinase, the resulting offspring will have the exon encoding this gene deleted in the cre-expressing tissue(s).

Mice

H11-CAG-EGFP

Strain Name：C57BL/6Smoc-Igs2 em1(CAG-EGFP-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00066

These mice harbor a CAG promoter-driven EGFP report gene. The targeted mutation was inserted into the Hipp11(H11) locus by homologous recombination.

Mice

Stat3-KO(in-frame mutation)

Strain Name：C57BL/6Smoc-Stat3emSmoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-210186

exon 18-20 of Stat3 gene was deleted to generate Stat3 knockout mice. The targeted knockout region mirrors that of the NM-CKO-200225 strain, with the experimental strategy designed according to published methodologies (PMID: 14566054; 17660847; 12571365).Lethality associated with this genetic modification has been documented. For details, click on the MGI ID in the genetic information.

Mice

Csf2-KO

Strain Name：C57BL/6Smoc-Csf2em2Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190532
Validation Data：Presence

Exon 1-3 of Csf2 gene was deleted to generate Csf2 knockout mice. Homozygotes for targeted null mutations exhibit lung abnormalities with lymphocytic infiltration and accumulation of surfactant lipids. Litter sizes from homozygous breeding pairs are smaller at weaning due to perinatal mortality (Note from MGI).

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