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H11-pThy1-hPSEN1-IRES-tdTomato

Strain Name：C57BL/6Smoc-Igs2^{em1(pThy1-PSEN1-IRES-tdTomato-WPRE-pA)Smoc}
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18049

A Thy1 promoter-PSEN1-IRES-tdTomato-WPRE-polyA cassette was knocked into the Igs2 locus (Hipp11 or H11; an intergenic region on chromosome 11 [cytoband A1 at ~3cM between the Eif4enif1 and Drg1 loci] reported to support high-level global gene expression in conjunction with the CAG (CAGGS) promoter and a higher rate of mitotic/interchromosomal recombination compared to Gt(ROSA)26Sor) .

H11-CAG-RSR-EYFP

Strain Name：C57BL/6Smoc-Igs2^{em1(CAG-RSR-EYFP)Smoc}
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-18056

A CAG-ROX-STOP-ROX-EYFP-V5tag-polyA conditional expression cassette was knocked into the Igs2 locus (Hipp11 or H11; an intergenic region on chromosome 11 [cytoband A1 at ~3cM between the Eif4enif1 and Drg1 loci] reported to support high-level global gene expression in conjunction with the CAG (CAGGS) promoter and a higher rate of mitotic/interchromosomal recombination compared to Gt(ROSA)26Sor) . This strain of mice can be used to mate with mice expressing the Dre recombinase. After exposure to Dre recombinase, expression of ellow fluorescent protein and V5 tag is observed for cell tracking.

Il3-KO

Strain Name：C57BL/6Smoc-Il3^em2Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190498

Exon 1-4 of Il3 gene was deleted to generate Il3 knockout mice.

Elmo1-KO

Strain Name：C57BL/6Smoc-Elmo1^em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190953

Exon 4 of Elmo1 gene was deleted to generate Elmo1 knockout mice.

Human foreskin fibroblast produces interleukin-6 to support derivation and self-renewal of mouse embryonic stem cells

Model Organisms：小鼠 Product & Service：- Research field：Stem Cell Research

"Biomodel Organism" Holds Ceremony in Beijing to Celebrate Listing on NEEQ

On November 18, 2016, Shanghai Model Organisms Center, Inc. was listed on the NEEQ as follows. Stock Name: Biomodel Organism; Stock Code: 839728.

Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

SMOC Received OLAW (Office of Laboratory Animal Welfare) Approval for Animal Welfare Assurance

Shanghai Model Organisms Center Inc.(SMOC) received the approval of Animal Welfare Assurance from the Office of Laboratory Animal Welfare (OLAW) of the U.S. National Institutes of Health (NIH) for its animal facility on January 25, 2021.

New Service Launch: Mouse Bone Metastasis Cancer Model and Pain-Related Behavior Assessment!

Bone metastasis cancer model Pain-related behavior assessment Cancer-induced bone pain Bone cancer pain models Mouse bone metastasis model Animal models in cancer research Cancer research services Bone metastasis in mice Pain management in cancer

We are excited to announce that GenoBioTX has launched a new service featuring mouse bone metastasis cancer models and pain-related behavior assessment, designed to support cancer research and pain management effectively.

Join Our Webinar: Advanced Strategies in Genetically Modified Mice

Discover cutting-edge strategies and applications of genetically modified mice in biomedical research at our webinar on May 23rd, 2024. Register now for insights from industry expert Dongxiao Feng