Welcome to Advanced Search

Acan-IRES-CreERT2

Strain Name：C57BL/6Smoc-Acan^{em1(IRES-CreERT2)Smoc}
Strain State：Repository Live | Cat. NO.：NM-KI-200143
Validation Data：Presence

A IRES-CreERT2 expression cassette was knocked into the Acan gene stop codon site via CRISPR/Cas9 mediated recombination.

Mir29a/Mir29b1-KO

Strain Name：C57BL/6Smoc-Mir29a^em1 Mir29b-1^em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-00081

a 0.6kb region in length including Mir29a and Mir29b-1 pre-microRNAs was removed in this strain.

Hdac4-KO

Strain Name：C57BL/6Smoc-Hdac4^em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00075

Exon 4 was removed.

huPBMC-(NMG)

Strain Name：huPBMC-(M-NSG)
Strain State：Repository Live | Cat. NO.：NM-NSG-015

NMG mice are injected with human peripheral blood mononuclear cells (huPBMCs).

huHSC-(NMG)

Strain Name：huHSC-(M-NSG)
Strain State：Repository Live | Cat. NO.：NM-NSG-017
Publications：2piece

After irradiation, NMG mice are injected with CD34+ hematopoietic stem cells (CD34+ HSC).

Polymorphisms of STAT4 and the risk of inflammatory bowel disease: A case-control study in Chinese Han population

Model Organisms：病人 Product & Service：STAT4 Research field：Digestive system

炎症性肠病( IBD) 汉族

Screening study on the anti-angiogenic effects of Traditional Chinese Medicine - Part I: Heat-clearing and...

Model Organisms：斑马鱼 Product & Service：- Research field：Drug screening and drug mechanism

血管生成抑制剂 血管生成 中药

New Service Launch: Mouse Bone Metastasis Cancer Model and Pain-Related Behavior Assessment!

Bone metastasis cancer model Pain-related behavior assessment Cancer-induced bone pain Bone cancer pain models Mouse bone metastasis model Animal models in cancer research Cancer research services Bone metastasis in mice Pain management in cancer

We are excited to announce that GenoBioTX has launched a new service featuring mouse bone metastasis cancer models and pain-related behavior assessment, designed to support cancer research and pain management effectively.

SMOC Launched U-HuDTMbase®, Inclusive Resource Library of Innovative Therapeutic Target-Humanized Mouse Models, to Accelerate Novel Drug Discovery

U-HuDTMbase® is composed of more than 600 therapeutic target-humanized mouse models, including multiple background strains, and has covered almost all commonly studied areas, such as oncology, metabolism, immunity, inflammation and more.

These Mice Are About to Go Viral Because of the Nobel Prize!

microRNA (miRNA) microRNA mouse models Nobel Prize microRNA discovery genetically engineered mice miRNA in gene regulation miRNA therapeutics miRNA in cancer research customized mouse models contract research organization (CRO) preclinical drug discovery

The 2024 Nobel Prize in Physiology or Medicine awarded to Victor Ambros and Gary Ruvkun for their discovery of microRNA (miRNA) highlights its revolutionary role in gene regulation and disease treatment. This article explores miRNA's impact on neuroscience, cancer, and cardiovascular research. GenoBioTX offers advanced microRNA mouse models and customized genetic solutions, empowering researchers with essential tools to drive innovation in miRNA studies and therapeutic developments.