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Models

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Mice

hCD81/hOCLN

Strain Name：C57BL/6Smoc-Cd81em1(hCD81)Oclnem1(hOCLN)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000107

These mice are obtained through breeding of two single gene humanized mice.

Mice

hDPP4

Strain Name：C57BL/6Smoc-Dpp4em1(DPP4)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190042

The endogenous mouse Dpp4 gene was replaced by human DPP4 gene.

Mice

NMG

Strain Name：NOD.Cg-PrkdcscidIl2rgem1Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-001

Prkdc and Il2rg genes were both knocked-out in NOD mice.  Lacking mature T, B and NK cells Low immune rejection against human cells and tissues Good tumorigenicity so that a small number of cells can form tumors. Significant improvement in the survival of transplanted human cells and tissues Suitable for the transplantation of human hematopoietic stem cells and the preparation of humanized mouse models Suitable as the carrier mice for the transplantation of heterologous cells and tissues

Mice

Fah-KO(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1Fahem2Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-NSG-004

Exon 3 of Fah gene was deleted to generate Fah knockout mice.

Mice

Lyzl4-KO

Strain Name：B6;129S-Lyzl4tm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00006

A Lyzl4 gene knockout strain.

Mice

hAppNL-G-F

Strain Name：C57BL/6Smoc-Apptm3(hAppNL-G-F)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000088

The endogenous mouse App gene was replaced by human AppNL-G-F.

Mice

Sav1-Flox

Strain Name：C57BL/6Smoc-Sav1tm1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200011

These mice carry loxP sites flanking exon 3 of Sav1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Sav1 gene.

Mice

Stk3-Flox

Strain Name：C57BL/6Smoc-Stk3em2(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200007

These mice carry loxP sites flanking exon 4 of Stk3 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Stk3 gene.

Mice

hAppNL-F

Strain Name：C57BL/6Smoc-Apptm3(hAppNL-F)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000087

The endogenous mouse App gene was replaced by human AppNL-F.

Mice

R26-CAG-LSL-hACE2-IRES-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-Loxp-stop-loxp-human ACE2-IRES-tdTomato-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200188

These mice harbor a SA-FRT-2xpolyA-CAG-FRT-Loxp-stop-loxp-human ACE2-IRES-tdTomato-WPRE-polyAA cassette in the Rosa26 locus generated by homologous recombination.

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