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Models

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Mice

hAppNL-G-F

Strain Name：C57BL/6Smoc-Apptm3(hAppNL-G-F)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000088

The endogenous mouse App gene was replaced by human AppNL-G-F.

Mice

hAppNL-F

Strain Name：C57BL/6Smoc-Apptm3(hAppNL-F)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000087

The endogenous mouse App gene was replaced by human AppNL-F.

Mice

R26-CAG-LSL-hACE2-IRES-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-Loxp-stop-loxp-human ACE2-IRES-tdTomato-WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200188

These mice harbor a SA-FRT-2xpolyA-CAG-FRT-Loxp-stop-loxp-human ACE2-IRES-tdTomato-WPRE-polyAA cassette in the Rosa26 locus generated by homologous recombination.

Mice

hTREM2

Strain Name：C57BL/6Smoc-Trem2em4(hTRem2)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000083

The endogenous mouse Trem2 gene was replaced by human TREM2 gene.

Mice

Aldob-KO

Strain Name：C57BL/6Smoc-Aldobem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200602

Exon 3-6 of Aldob gene was deleted to generate Aldob knockout mice.

Mice

Fah-KO(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1Fahem2Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-NSG-004

Exon 3 of Fah gene was deleted to generate Fah knockout mice.

Mice

Fah-KO

Strain Name：C57BL/6Smoc-Fahem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-191202

Partial exon 8 of Fah gene was deleted to generate Fah knockout mice.

Mice

Btd-KO

Strain Name：C57BL/6Smoc-Btdem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200630

Exon 2-3 of Btd gene was deleted to generate Btd knockout mice.

Mice

4-1BB-KO

Strain Name：C57BL/6Smoc-Tnfrsf9em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00088

Exon2 of Tnfrsf9 (4-1BB) gene was deleted to generate Tnfrsf9 (4-1BB) knockout mice.

Mice

H11-CAG-LSL-hACHE

Strain Name：C57BL/6Smoc-Igs2em1(CAG-LSL-ACHE-WPRE-pA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00067

These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven ACHE gene. The targeted mutation was inserted into the Hipp11(H11) locus by homologous recombination. ACHE is expressed when bred to mice that express Cre recombinase.

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