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Models

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Mice

Trem2-Flox

Strain Name：C57BL/6Smoc-Trem2tm2(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-190063

These mice carry loxP sites flanking exon 2-3 of Trem2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Trem2 gene.

Mice

Trem2-R47H

Strain Name：C57BL/6Smoc-Trem2em3(p.R47H)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190092

These mice carry a p.R47H mutation of Trem2 gene.

Mice

Ldlr-KO

Strain Name：C57BL/6Smoc-Ldlrem3Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190559

Ldlr-KO mice(Stock No.NM-KO-190559) carry a knockout allele derived from the targeted deletion of exon 6-10. While Ldlr-KO(2) mice(Stock No.NM-KO-210198) carrying the exon 4 deletion.

Mice

R26-CAG-LSL-hMET-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-c-MET-IRES-luciferase-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18052

A SA-2xpolyA-CAG-Loxp-Stop-Loxp-human cMET-IRES-luciferase-2A-tdTomato-wpre-polyA cassette was knocked into the mouse Rosa26 locus . This strain of mice can be mated with mice expressing Cre recombinase so that human C-MET could be expressed after exposure to Cre recombinase.

Mice

R26-LSL-hEZH2-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-EZH2-IRES-luciferase-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18053

A SA-2xpolyA-CAG-Loxp-Stop-Loxp-human EZH2 cDNA-IRES-luciferase-2A-tdTomato-wpre-polyA cassette was knocked into the mouse Rosa26 locus . This strain of mice can be mated with mice expressing Cre recombinase so that human EZH2 could be expressed after exposure to Cre recombinase.

Mice

R26-CAG-LSL-hNRF2-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-NRF2-IRES-luciferase-2A-tdTomato)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-18050

A SA-2xpolyA-CAG-LSL-human NRF2-IRES-luciferase-2A-tdTomato-wpre-polyA cassette was knocked into the mouse Rosa26 locus . This strain of mice can be mated with mice expressing Cre recombinase to express human NRF2 and a reporter gene in certain cells or tissues that expressing Cre recombinase.

Mice

Soat1-Flox

Strain Name：C57BL/6Smoc-Soat1tm1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-190064

These mice carry loxP sites flanking exon4 of Soat1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Soat1 gene.

Mice

Katnal2-KO

Strain Name：C57BL/6Smoc-Katnal2em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191190

Exon 3 of Katnal2 gene was deleted to generate Katnal2 knockout mice.

Mice

Tmem158-Flox

Strain Name：C57BL/6Smoc-tmem158tm1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200009

These mice carry loxP sites flanking exon 1 of Tmem158 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Tmem158 gene.

Mice

Gabra4-KO

Strain Name：C57BL/6Smoc-Gabra4em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190572

Exon 2 of Gabra4 gene was deleted to generate Gabra4 knockout mice.

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