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Models

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Mice

R26-CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luc

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luciferase)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200257

A CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luciferase expression cassette was knocked into the Rosa26 locus.

Mice

hHBB

Strain Name：C57BL/6Smoc-Hbb-bt&Hbb-bstm1(hHBB)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000080

The endogenous mouse Hbb-bt and Hbb-bs gene was replaced by human HBB gene.

Mice

hPD-L1/h4-1BB(2)

Strain Name：C57BL/6Smoc-Cd274em1(hPD-L1)Tnfrsf9tm2(h4-1BB)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200260

hPD-L1(NM-HU-00062) was crossed with h4-1BB(2)(NM-HU-190077) to generate hPD-L1/h4-1BB(2).

Mice

hSIRPA/hCD47(BALB/c)

Strain Name：BALB/cAnSmoc-Sirpatm4(hSIRPA)/SmocCd47em1(hCD47)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210020

hCD47 (NM-HU-00050) and hSRPA(2)(NM-HU-18015) were bred with BALB/c mice respectively to generate hSIRPA/hCD47(BALB/c) mice.

Mice

hPD-1/hIL1B

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Il1btm3(hIL1B)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210018

hPD-1(NM-HU-00015) was crossed with hIL1B(NM-HU-190047) to generate hPD-1/hIL1B mice

Mice

hPD-1/hLAG3/hTIGIT

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Lag3em1(hLAG3)Tigitem1(hTIGIT)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200258

hPD-1(NM-HU-00015),hTIGIT(NM-HU-00053) were crossed with hLAG3(NM-HU-00049) to generate hPD-1/hLAG3/hTIGIT.

Mice

Uox-KO(2)

Strain Name：C57BL/6Smoc-Uoxem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-191205

Uox-KO(2) mice(Stock No.NM-KO-191205）carry a knockout allele derived from the targeted deletion of exon 3-4.

Mice

hHLA-E

Strain Name：C57BL/6Smoc-Igs2em1(hHLA-E)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200221

The endogenous human HLA-E gene (about 11kb) was knocked into the H11 locus via CRISPR/Cas9 mediated recombination.

Mice

Gabra1-KO

Strain Name：C57BL/6Smoc-Gabra1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190570

Exon 4 of Gabra1 gene was deleted to generate Gabra1 knockout mice.

Mice

Galt-KO

Strain Name：C57BL/6Smoc-Galtem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200600

Exon 3-9 of Galt gene was deleted to generate Galt knockout mice.

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