Therapeutic Target-Humanized Mice
Cre/Dre-Driver Mice
Immunodeficient NMG Mice
Strain Name:C57BL/6Smoc-Tslptm2(hTSLP)/Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000064 Validation Data:Presence
The endogenous mouse Tslp gene was replaced by human TSLP gene.
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luciferase)Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200257
A CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luciferase expression cassette was knocked into the Rosa26 locus.
Strain Name:BALB/cAnSmoc-Sirpatm4(hSIRPA)SmocCd47tm1(hCD47)Smoc Strain State:Repository Live | Cat. NO.:NM-HU-210020 Validation Data:Presence
hCD47 (NM-HU-00050) and hSRPA(2)(NM-HU-18015) were bred with BALB/c mice respectively to generate hSIRPA/hCD47(BALB/c) mice.
Strain Name:C57BL/6Smoc-Cd274tm1(hPD-L1)Tnfrsf9tm2(h4-1BB)Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200260
hPD-L1(NM-HU-00062) was crossed with h4-1BB(2)(NM-HU-190077) to generate hPD-L1/h4-1BB(2).
Strain Name:C57BL/6Smoc-Uoxem1Smoc Strain State:Repository Live | Cat. NO.:NM-KO-191205 Validation Data:Presence | Publications:1piece
Uox-KO(2) mice(Stock No.NM-KO-191205)carry a knockout allele derived from the targeted deletion of exon 3-4.
Strain Name:C57BL/6Smoc-Pdcd1tm1(hPDCD1)Il1btm3(hIL1B)Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210018
hPD-1(NM-HU-00015) was crossed with hIL1B(NM-HU-190047) to generate hPD-1/hIL1B mice
Strain Name:C57BL/6Smoc-Pdcd1tm1(hPDCD1)Lag3tm1(hLAG3)Tigittm1(hTIGIT)Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200258
hPD-1(NM-HU-00015),hTIGIT(NM-HU-00053) were crossed with hLAG3(NM-HU-00049) to generate hPD-1/hLAG3/hTIGIT.
Strain Name:C57BL/6Smoc-Gabra1em1Smoc Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-190570
Exon 4 of Gabra1 gene was deleted to generate Gabra1 knockout mice.
Strain Name:C57BL/6Smoc-Igs2tm1(hHLA-E)Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200221
The endogenous human HLA-E gene (about 11kb) was knocked into the H11 locus via CRISPR/Cas9 mediated recombination.
Strain Name:C57BL/6Smoc-Galtem1Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200600
Exon 3-9 of Galt gene was deleted to generate Galt knockout mice.
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