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Models

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Mice

Wrn-KO

Strain Name:C57BL/6Smoc-Wrnem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-190902

Exon 5-8 of Wrn gene was deleted to generate Wrn knockout mice.

Mice

Ptf1a-CreERT2

Strain Name:C57BL/6Smoc-Ptf1aem1(CreERT2-WPRE-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200118

A CreERT2-WPRE-pA expression cassette was knocked into the Ptf1a gene start codon site.

Mice

Adrb3-KO

Strain Name:C57BL/6Smoc-Adrb3em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-190739

Exon 2 of Adrb3 gene was deleted to generate Adrb3 knockout mice.

Mice

Agt-KO

Strain Name:C57BL/6Smoc-Agtem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-190740

Exon 2-5 of Agt gene was deleted to generate Agt knockout mice.

Mice

Col1a1-IRES-CreERT2

Strain Name:C57BL/6Smoc-Col1a1em(IRES-CreERT2)1Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-225031

IRES-CreERT2 expression cassette was knocked into the Col1a1 gene. The strain cannot breed homozygotes, and it is recommended to use heterozygotes for research.

Mice

Col2a1-2A-CreERT2

Strain Name:C57BL/6Smoc-Col2a1em1(2A-CreERT2)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-18029

A 2A-CreERT2 expression cassette was knocked into the stop codon of Col2a1 gene to establish a Col2a1-CreERT2 recombinase tool mouse.The strain cannot breed homozygotes, and it is recommended to use heterozygotes for research.

Mice

Col1a1-IRES-EGFP-IRES-MerCreMer

Strain Name:C57BL/6Smoc-Col1a1em1(IRES-EGFP-IRES-MerCreMer)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-240492

The IRES-EGFP-IRES-MerCreMer expression cassette was knocked into the Col1a1 gene stop codon site. The strain cannot breed homozygotes, and it is recommended to use heterozygotes for research.

Mice

Etv1-CreERT2

Strain Name:C57BL/6Smoc-Etv1em1(CreERT2-SV40-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200105

A CreERT2 expression cassette was knocked into the Etv1 gene start codon site. ETV1 expression is enriched in fast conduction tissues of embryonic and adult mammalian hearts. And ETV1 expression is upregulated in the atrial tissue of patients with permanent atrial fibrillation. Etv-CreERT2 mice can be applied to heart disease research. ETV1 is also expressed in retinal ganglion cells of adult mice, and the mouse model can be used to study how retinal ganglion cells contribute to visual processing in the brain.

Mice

C57BL/6

Strain Name:C57BL/6Smoc
Strain State:Repository Live | Cat. NO.:SM-001

C57BL/6 mice have a high reproductive capacity, a long life span, and a low tumor susceptibility. Male mice are aggressive and fight frequently. Diet can cause obesity, type II diabetes, and atherosclerosis in these mice. The C57BL/6 mouse is the first to have its entire genome sequenced. It is the most extensively used inbred mouse strain as a genetic basis for congenic and mutant mice. It is also used in genetics, metabolism, immunology, neurology, behavioral research, pharmacodynamics, and medication safety evaluation.

Mice

R26-CAG-LSL-mTurquoise2-SLBP(18-126)-2A-H1-mMaroon1

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpA-CAG-FRT-loxp-STOP-loxp-mTurquoise2-SLBP(18-126)-P2A-H1-mMaroon1-WPRE-pA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200007

These mice harbor a SA-Frt-2xpolyA-CAG-Frt-LSL-mTurquoise2-SLBP(18-126)-P2A-H1-mMaroon1-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination.

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