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Mice

Agt-KO

Strain Name:C57BL/6Smoc-Agtem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-190740

Exon 2-5 of Agt gene was deleted to generate Agt knockout mice.

Mice

Col2a1-2A-CreERT2

Strain Name:C57BL/6Smoc-Col2a1em1(2A-CreERT2)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-18029

A 2A-CreERT2 expression cassette was knocked into the stop codon of Col2a1 gene to establish a Col2a1-CreERT2 recombinase tool mouse.The strain cannot breed homozygotes, and it is recommended to use heterozygotes for research.

Mice

Etv1-CreERT2

Strain Name:C57BL/6Smoc-Etv1em1(CreERT2-SV40-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200105

A CreERT2 expression cassette was knocked into the Etv1 gene start codon site. ETV1 expression is enriched in fast conduction tissues of embryonic and adult mammalian hearts. And ETV1 expression is upregulated in the atrial tissue of patients with permanent atrial fibrillation. Etv-CreERT2 mice can be applied to heart disease research. ETV1 is also expressed in retinal ganglion cells of adult mice, and the mouse model can be used to study how retinal ganglion cells contribute to visual processing in the brain.

Mice

C57BL/6

Strain Name:C57BL/6Smoc
Strain State:Repository Live | Cat. NO.:SM-001

C57BL/6 mice have a high reproductive capacity, a long life span, and a low tumor susceptibility. Male mice are aggressive and fight frequently. Diet can cause obesity, type II diabetes, and atherosclerosis in these mice. The C57BL/6 mouse is the first to have its entire genome sequenced. It is the most extensively used inbred mouse strain as a genetic basis for congenic and mutant mice. It is also used in genetics, metabolism, immunology, neurology, behavioral research, pharmacodynamics, and medication safety evaluation.

Mice

R26-CAG-LSL-mTurquoise2-SLBP(18-126)-2A-H1-mMaroon1

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpA-CAG-FRT-loxp-STOP-loxp-mTurquoise2-SLBP(18-126)-P2A-H1-mMaroon1-WPRE-pA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200007

These mice harbor a SA-Frt-2xpolyA-CAG-Frt-LSL-mTurquoise2-SLBP(18-126)-P2A-H1-mMaroon1-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination.

Mice

R26-CAG-LSL-Clover-Geminin(1-110)-2A-mKO2-Cdt(30-120)

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpA-CAG-FRT-loxp-STOP-loxp-Clover-Geminin(1-110)-P2A-mKO2-Cdt(30-120)-WPRE-PA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200008

These mice harbor a SA-FRT-2xpA-CAG-FRT-loxp-STOP-loxp-Clover-Geminin(1-110)-P2A-mKO2-Cdt(30-120)-WPRE-PA cassette in the Rosa26 locus generated by homologous recombination.

Mice

hTLR8/Lyz2-DTREGFP

Strain Name:C57BL/6Smoc-Lyz2em3(IRES-DTREGFP)Tlr8tm2(TLR8)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200259

NM-KI-190041 was crossed with NM-HU-190044 to generate hTLR8/Lyz2-IRES-DTREGFP mice.

Mice

hGLP1R

Strain Name:C57BL/6Smoc-Glp1rem2(hGLP1R)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-200220

The endogenous mouse Glp1r gene was completely or partially replaced by human hGLP1R gene via CRISPR/Cas9 mediated recombination.

Mice

hPD-L1/hCD28

Strain Name:C57BL/6Smoc-Cd274em1(hPD-L1)Cd28em2(hCD28)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210019

hPD-L1(NM-HU-00062) was crossed with hCD28(NM-HU-190011) to generate hPD-L1/hCD28 mice

Mice

hTSLP

Strain Name:C57BL/6Smoc-Tslptm2(hTSLP)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000064

The endogenous mouse Tslp gene was replaced by human TSLP gene.

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