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Models

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Mice

hVISTA

Strain Name：C57BL/6Smoc-Vsirtm1(hVSIR)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00118
Validation Data：Presence

The exon 2-3 of endogenous mouse Vsir gene was replaced by the exon 2-3 of human VSIR(VISTA) gene.

Mice

hTIGIT

Strain Name：C57BL/6Smoc-Tigittm1(hTIGIT)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00053
Validation Data：Presence

The endogenous mouse Tigit gene was replaced by human TIGIT gene. While hTIGIT(3)(Stock No.NM-HU-200244) mice function similarly to hTIGIT mice,for more detailed information please contact our technical advisor.

Mice

hCD79B

Strain Name：C57BL/6Smoc-Cd79btm2(hCD79B )Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000012
Validation Data：Presence

The endogenous mouse Cd79b gene was replaced by human CD79B gene.

Mice

hB7H4(2)

Strain Name：C57BL/6Smoc-Vtcn1tm2(hVTCN1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190075

Extracellular domain of mouse Vtcn1 gene was replaced by human VTCN1 gene. While hB7H4(Stock No.NM-HU-190004) mice function similarly to hB7H4(2) mice,for more detailed information please contact our technical advisor.

Mice

hSTING

Strain Name：C57BL/6Smoc-Tmem173tm2(hTMEM173)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190036
Validation Data：Presence

The endogenous mouse Tmem173 gene was replaced by human TMEM173 gene.

Mice

hLAG3

Strain Name：B6.129S-Lag3tm1(hLAG3)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00049
Validation Data：Presence

The endogenous mouse Lag3 gene exon1-7 was replaced by human LAG3 gene extracellular region by homologous recombination.

Mice

hIL9

Strain Name：C57BL/6Smoc-Il9tm3(hIL9)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-18029
Validation Data：Presence

The endogenous mouse Il9 gene was replaced by human IL9 gene .

Mice

hCD160

Strain Name：C57BL/6Smoc-Cd160tm1(CD160)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190057

The endogenous mouse Cd160 gene was replaced by human CD160 gene.

Mice

hFCRN(NMG)

Strain Name：NOD.Cg-PrkdcscidIl2rgem1Fcgrttm2(FCGRT)Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-020
Validation Data：Presence

The background of this strain is NMG, and its endogenous Fcgrt gene is replaced with human FCGRT.

Mice

hSEMA4D

Strain Name：C57BL/6Smoc-Sema4dtm1(hSEMA4D)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00117
Validation Data：Presence

The endogenous mouse Sema4d gene was replaced by human SEMA4D gene.

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