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Models

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Mice

hTLR8

Strain Name:C57BL/6Smoc-Tlr8tm2(TLR8)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190044

The endogenous mouse Tlr8 gene was replaced by human TLR8 gene.

Mice

hPD-1/hPD-L1/hOX40

Strain Name:C57BL/6Smoc-Tnfrsf4em3(hTNFRSF4)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00122

hPD-1(NM-HU-00015),hPD-L1(NM-HU-00062) were crossed with hOX40(NM-HU-00041) to generate hPD-1/hPD-L1/hOX40.

Mice

hCD3E

Strain Name:C57BL/6Smoc-Cd3eem1(hCD3E) Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00114

The endogenous mouse Cd3e gene was replaced by human CD3E gene . While hCD3E(2)(Stock No.NM-HU-210023) mice function similarly to hCD3E mice,for more detailed information please contact our technical advisor.

Mice

hHGF(NOD-scid)

Strain Name:NOD-PrkdcscidHgfem1(hHGF)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190062

The endogenous mouse Hgf gene was replaced by human HGF gene.

Mice

hCCR1

Strain Name:C57BL/6Smoc-Ccr1em3(hCCR1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190067

The endogenous mouse Ccr1 gene was replaced by human CCR1 gene.

Mice

hCD27(2)

Strain Name:C57BL/6Smoc-Cd27tm3(hCD27)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190035

The endogenous mouse Cd27 gene was replaced by human CD27 gene. While hCD27 mice(Stock No.NM-HU-00093)have been pulled from shelves for some reasons.

Mice

hTIGIT

Strain Name:C57BL/6Smoc-Tigitem1(hTIGIT)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00053

The endogenous mouse Tigit gene was replaced by human TIGIT gene. While hTIGIT(3)(Stock No.NM-HU-200244) mice function similarly to hTIGIT mice,for more detailed information please contact our technical advisor.

Mice

hBTLA(2)

Strain Name:C57BL/6Smoc-Btlaem2(hBTLA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190040

Extracellular domain of mouse Btla gene was replaced by human BTLA gene. While hBTLA mice(Stock No.NM-HU-18014)have been pulled from shelves for some reasons.

Mice

hVISTA

Strain Name:C57BL/6Smoc-Vsirem1(hVSIR)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00118

The exon 2-3 of endogenous mouse Vsir gene was replaced by the exon 2-3 of human VSIR(VISTA) gene.

Mice

hCSF1

Strain Name:C57BL/6Smoc-Csf1tm2(CSF1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190043

The endogenous mouse Csf1 gene was replaced by human CSF1 gene.

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