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Models

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Mice

Stat3-Flox

Strain Name：C57BL/6Smoc-Stat3tm7(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200050

These mice carry loxP sites flanking exon 12-14 of Stat3 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Stat3 gene.While Stat3-Flox(in-frame mutation)(Stock No.NM-CKO-200225）mice carrying the loxP sites flanking exon 18-20 of Stat3 gene.

Mice

R26-CAG-LSL-hEGFR*T790M-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-LSL-EGFR (T790M) -IRES-Luciferase-2A-tdTomato)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190070

These mice harbor a CAG-LSL-EGFR(T790M)-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.

Mice

Trp53-KO(2)

Strain Name：C57BL/6Smoc-Trp53em5Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191203

Exon 5-7 of Trp53 gene was deleted to generate Trp53 knockout mice.

Mice

Mycn-TRE-EGFP

Strain Name：B6;129S-Mycntm1(TRE-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00008

A TRE site and a loxp EGFP casette were inserted into introns 1-2 to create a Dox-inducible N-myc gene silence mice.

Mice

H11-CAG-LSL-LSL-hMYCN-IRES-EGFP

Strain Name：C57BL/6Smoc-Igs2tm1(CAG-loxp-Neo-Stop-loxp-lox2272-Neo-Stop-lox2272-HA tag-NMYC-IRES-EFGP-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-210145

A CAG-loxp-Neo-Stop-loxp-lox2272-Neo-Stop-lox2272-HA tag-NMYC-IRES-EFGP-WPRE-polyA expression cassette was knocked into via the lgs2 (H11) locus.

Mice

Nf2-Flox

Strain Name：C57BL/6Smoc-Nf2tm1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200017

These mice carry loxP sites flanking exon 2 of Nf2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Nf2 gene.

Mice

Cdkn2a-Flox(p16/p19-Flox)

Strain Name：C57BL/6Smoc-Cdkn2aem3(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200015
Publications：1piece

These mice carry loxP sites flanking exon 2 of the common region of Cdkn2a-p19ARF and Cdkn2a-p16INK4a transcripts.

Mice

Zmynd8-KO

Strain Name：C57BL/6Smoc-Zmynd8em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190563

Exon 3-4 of Zmynd8 gene was deleted to generate Zmynd8 knockout mice.

Mice

R26-CAG-LSL-hRHOA*Y42C-IRES-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(SA-FRT-2xpolyA-CAG-FRT-LSL-RHOA(Y42C)-IRES-tdTomato-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200048

These mice harbor a SA-FRT-2xpolyA-CAG-FRT-RHOA(Y42C)-IRES-tdTomato-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination.

Mice

Egfr-Flox

Strain Name：C57BL/6Smoc-Egfrem1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-00133

These Egfr flox mice possess loxP sites flanking exons 19. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

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