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Mice

Apc-L850X

Strain Name：C57BL/6Smoc-Apcem1(L850X)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200001

Familial adenomatous polyposis (FAP) is a heritable condition in which affected individuals develop benign intestinal polyps. Often, polyps progress to colorectal carcinomas later in life. The mutation of C57BL/6-Apcem1(L850X)Smoc(NM-KI-200001) strain of SMOC refers to the ApcMin model (Jax: 002020 ), a useful model to study intestinal adenomas. The C57BL/6-Apcem1(L850X)Smoc strain is highly susceptible to spontaneous intestinal adenoma formation and can be used as a research model for human FAP. These mice carry a p.L850X mutation of Apc gene.

Mice

Eomes-Flox

Strain Name：C57BL/6Smoc-Eomesem1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200162

These mice carry loxP sites flanking exon 2 of Eomes gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Eomes gene.

Mice

Il6ra-Flox(2)

Strain Name：C57BL/6Smoc-Il6raem2(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-200188

These mice carry loxP sites flanking exon 4-6 of Il6ra gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Il6ra gene.While Il6ra-Flox(2)(Stock No.NM-CKO-200318) mice

Mice

Chat-Flox

Strain Name：C57BL/6Smoc-Chatem1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200153

These mice carry loxP sites flanking exon 4-5 of Chat gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Chat gene.

Mice

Dgcr8-Flox

Strain Name：C57BL/6Smoc-Dgcr8em1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200157

These mice carry loxP sites flanking exon 3 of Dgcr8 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Dgcr8 gene.

Mice

Smo-Flox

Strain Name：C57BL/6Smoc-Smoem1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200221

These mice carry loxP sites flanking exon 2-8 of Smo gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Smo gene.

Mice

Itgb3-Flox

Strain Name：C57BL/6Smoc-Itgb3em1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200111

These mice carry loxP sites flanking exon 1 of Itgb3 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Itgb3 gene.

Mice

Cxcl12-Flox

Strain Name：C57BL/6Smoc-Cxcl12em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200155

These mice carry loxP sites flanking exon 2 of Cxcl12 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Cxcl12 gene.

Mice

Il1r1-Flox

Strain Name：C57BL/6Smoc-Il1r1em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-200105

These mice carry loxP sites flanking exon 3-4 of Il1r1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Il1r1 gene.

Mice

Ngfr-Flox

Strain Name：C57BL/6Smoc-Ngfrtm1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200170

These mice carry loxP sites flanking exon 4-6 of Ngfr gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Ngfr gene.

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