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Models

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Mice

Rela-Flox

Strain Name：C57BL/6Smoc-Relaem1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200213

These mice carry loxP sites flanking exon 1 of Rela gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Rela gene.

Mice

hFCRN

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-hFcRn)Fcgrtem1/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00109

This FcRn humanized strain is established by mating endogenous mouse Fcgrt gene Knockout mice with R26-hFcRn(FCGRT) Knock-in mice. These FcRn humanized mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations. While hFCRN(2)(Stock No.NM-HU-190070) and hFCRN(3)(Stock No.NM-HU-2000032）mice function similarly to hFCRN mice,for more detailed information please contact our technical advisor.

Mice

Rpa1-Flox

Strain Name：C57BL/6Smoc-Rpa1tm1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200042

These mice carry loxP sites flanking exon 8 of Rpa1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Rpa1 gene.

Mice

R26-CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luc

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luciferase)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200257

A CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luciferase expression cassette was knocked into the Rosa26 locus.

Mice

Runx3-Flox

Strain Name：C57BL/6Smoc-Runx3tm2(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-200028

These mice carry loxP sites flanking exon 3 of Runx3 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Runx3 gene.

Mice

hCD80

Strain Name：C57BL/6Smoc-Cd80em1(hCD80) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00074

The endogenous mouse Cd80 gene was replaced by human CD80 gene .

Mice

Ranbp2-Flox

Strain Name：C57BL/6Smoc-Ranbp2tm1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200030

These mice carry loxP sites flanking exon 3 of Ranbp2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Ranbp2 gene.

Mice

Pms2-Flox

Strain Name：C57BL/6Smoc-Pms2em1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200040

These mice carry loxP sites flanking exon 7 of Pms2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Pms2 gene.

Mice

hPD-1/hCTLA-4

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Ctla4em1(hCTLA4)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00079

hPD-1(NM-HU-00015) was crossed with hCTLA4(NM-HU-00014)to generate hPD-1/hCTLA4 mice

Mice

Trp53-Flox

Strain Name：C57BL/6Smoc-Trp53tm2(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-18005

These Trp53 flox mice possess loxP sites flanking exons 5-7 via ESC targeting. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

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