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Models

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Mice

Pten-KO

Strain Name：C57BL/6Smoc-Ptenem3Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18002

Exon5 of Pten gene was deleted to generate Pten knockout mice.

Mice

hCTLA-4

Strain Name：C57BL/6Smoc-Ctla4em1(hCTLA4) Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00014

The endogenous mouse Ctal4 gene was replaced by human CTLA4 gene. While hCTLA4(2)(Stock No.NM-HU-190038) mice function similarly to hCTLA4 mice,for more detailed information please contact our technical advisor.

Mice

Braf-Flox-V600E

Strain Name：C57BL/6Smoc-Brafem1(flox-V600E)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190053

These mice carry a conditional p.V600E mutation of Braf gene.

Mice

hPD-L1/hCD28

Strain Name：C57BL/6Smoc-Cd274em1(hPD-L1)Cd28em2(hCD28)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210019

hPD-L1(NM-HU-00062) was crossed with hCD28(NM-HU-190011) to generate hPD-L1/hCD28 mice

Mice

hTSLP

Strain Name：C57BL/6Smoc-Tslptm2(hTSLP)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000064

The endogenous mouse Tslp gene was replaced by human TSLP gene.

Mice

R26-CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luc

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luciferase)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200257

A CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luciferase expression cassette was knocked into the Rosa26 locus.

Mice

Trp53-Flox

Strain Name：C57BL/6Smoc-Trp53tm2(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-18005

These Trp53 flox mice possess loxP sites flanking exons 5-7 via ESC targeting. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

hPD-1/hOX40

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Tnfrsf4em3(hTNFRSF4) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00108

hPD-1（NM-HU-00015）was crossed with hOX40（NM-HU-00041）to generate hPD-1/hOX40.

Mice

hHBB

Strain Name：C57BL/6Smoc-Hbb-bt&Hbb-bstm1(hHBB)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000080

The endogenous mouse Hbb-bt and Hbb-bs gene was replaced by human HBB gene.

Mice

hPD-L1/hOX40

Strain Name：C57BL/6Smoc-Cd274em1(hPD-L1)Tnfrsf4em1(hTNFRSF4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00111

hPD-L1（NM-HU-00062）was crossed with hOX40（NM-HU-00041）to generate hPD-L1/hOX40.

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