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Mice

Adrb3-KO

Strain Name：C57BL/6Smoc-Adrb3em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190739

Exon 2 of Adrb3 gene was deleted to generate Adrb3 knockout mice.

Mice

Agt-KO

Strain Name：C57BL/6Smoc-Agtem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190740

Exon 2-5 of Agt gene was deleted to generate Agt knockout mice.

Mice

BALB/c

Strain Name：BALB/cAnSmoc
Strain State：Repository Live | Cat. NO.：SM-003

BALB/c is one of the most widely used inbred lines in biomedical research, especially in immunology and infectious disease research. The incidence of breast tumors is about 10% to 20%. There is a certain number of ovarian, adrenal, pulmonary tumors, and leukemia that occurs. Lung cancer occurs in 26% of female mice and 29% of male mice. The incidence of leukemia is 12% in females and 10% in males. Blood pressure was the highest compared to other inbred mice and had spontaneous hypertension.

Mice

hCD98(V1)

Strain Name：C57BL/6Smoc-Slc3a2tm1(hSLC3A2)Smoc
Strain State：Developing | Cat. NO.：NM-HU-253946

The endogenous mouse Slc3a2 gene was replaced by human SLC3A2 gene.This strain contains a humanized 3'UTR and can be used for small nucleic acid drug research.

Mice

Col1a1-IRES-CreERT2

Strain Name：C57BL/6Smoc-Col1a1em(IRES-CreERT2)1Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-225031
Validation Data：Presence

IRES-CreERT2 expression cassette was knocked into the Col1a1 gene. The strain cannot breed homozygotes, and it is recommended to use heterozygotes for research.

Mice

Col2a1-2A-CreERT2

Strain Name：C57BL/6Smoc-Col2a1em1(2A-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18029
Validation Data：Presence  |  Publications：1piece

A 2A-CreERT2 expression cassette was knocked into the stop codon of Col2a1 gene to establish a Col2a1-CreERT2 recombinase tool mouse.The strain cannot breed homozygotes, and it is recommended to use heterozygotes for research.

Mice

Col1a1-IRES-EGFP-IRES-MerCreMer

Strain Name：C57BL/6Smoc-Col1a1em1(IRES-EGFP-IRES-MerCreMer)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-240492
Validation Data：Presence

The IRES-EGFP-IRES-MerCreMer expression cassette was knocked into the Col1a1 gene stop codon site. The strain cannot breed homozygotes, and it is recommended to use heterozygotes for research.

Mice

Col1a1-tetO-EML4-ALK

Strain Name：C57BL/6Smoc-Col1a1tm1(TetO-EML4-ALK)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：DM-KI-251860

The human EML4-ALK gene was cloned into a TetO-EML4-ALK construct and microinjected into FVB zygotes, where it was inserted into the mouse Col1a1 locus. This strain was donated by the laboratory of Academician Liang Chen at Jinan University. Any published research papers or other forms of literature should cite: "Zhou Q, Yang T, Yu X, et al. Lanatoside C activates the E3 ligase STUB1 to inhibit FOXP3 transcriptional activity and promote antitumor immunity. EMBO Mol Med. 2025;17(3):563-588. doi:10.1038/s44321-025-00200-y"

Mice

Etv1-CreERT2

Strain Name：C57BL/6Smoc-Etv1em1(CreERT2-SV40-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200105
Validation Data：Presence

A CreERT2 expression cassette was knocked into the Etv1 gene start codon site. ETV1 expression is enriched in fast conduction tissues of embryonic and adult mammalian hearts. And ETV1 expression is upregulated in the atrial tissue of patients with permanent atrial fibrillation. Etv-CreERT2 mice can be applied to heart disease research. ETV1 is also expressed in retinal ganglion cells of adult mice, and the mouse model can be used to study how retinal ganglion cells contribute to visual processing in the brain.

Mice

Nkx2-1-CreERT2

Strain Name：C57BL/6Smoc-Nkx2-1em1(CreERT2-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200123
Validation Data：Presence

A CreERT2-pA expression cassette was knocked into the Nkx2-1 gene start codon site. Nkx2-1, a key molecule in lung development, is expressed in adult bronchial and alveolar type Ⅱ epithelial cells. Besides, Nkx2-1 expression as a prognostic marker is also been applied to lung cancer research including lung adenocarcinoma.

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