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Mice

R26-CAG-LSL-Luc-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-luci-2A-tdTomato)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18051

A CAG-loxP STOP-loxP-luci-2A-tdTomato-WPRE-polyA cassette was knocked into the mouse ROSA26 locus . This strain of mice can be mated with mice expressing Cre recombinase so that luciferase and tdTomato fluorescent protein could be expressed for cell tracing.

Mice

MHC Class II(I-A/I-E)-KO(Nod-Scid)

Strain Name：NOD-PrkdcscidH2-Ab1em1H2-Aaem1H2-Eb1em1H2-Eb2em1H2-Ea-psem1Smoc
Strain State：Developing | Cat. NO.：NM-KO-18057

All sequences from the upstream of mouse H2-Ab1 gene exon 2 to the upstream of the H2-Ea-ps gene exon 1 were knocked out to obtain H2-Ab1、H2-Aa、H2-Eb1、H2-Eb2、H2-Ea-ps knockout mouse models. These MHC class II molecule-deficient mice were on the Nod-Scid genetic background and lacked cell surface expression of both class II-A and class II-E MHC proteins.

Mice

MHC ClassII(I-A/I-E)-KO(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1H2-Ab1em1H2-Aaem1H2-Eb1em1H2-Eb2em1H2-Ea-ps em1Smoc
Strain State：Developing | Cat. NO.：NM-NSG-003

All sequences from the upstream of  mouse H2-Ab1 gene exon 2  to the upstream of the H2-Ea-ps gene  exon 1 were knocked out to obtain H2-Ab1、H2-Aa、H2-Eb1、H2-Eb2、H2-Ea-ps knockout mouse models.  These MHC class II molecule-deficient mice were on the NMG genetic background and also lacked cell surface expression of both class II-A and class II-E MHC proteins.

Mice

MHC Class II (I-A/I-E) -KO

Strain Name：C57BL/6Smoc-H2-Ab1em1H2-Aaem1 H2-Eb1em1H2-Eb2em1H2-Ea-ps em1 Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18032

All sequences from the upstream of mouse H2-Ab1 gene exon 2 to the upstream of the H2-Ea-ps gene exon 1 were knocked out to obtain H2-Ab1、H2-Aa、H2-Eb1、H2-Eb2、H2-Ea-ps knockout mouse models. These MHC class II molecule-deficient mice were on the C57BL/6J genetic background and also lacked cell surface expression of both class II-A and class II-E MHC proteins.

Mice

MHCII/B2m-KO(NMG)

Strain Name：NOD.Cg-PrkdcscidIl2rgem1H2-Ab1em1H2-Aaem1H2-Eb1em1H2-Eb2em1H2-Ea-ps em1B2m em1Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-014

All sequences from the upstream of  mouse H2-Ab1 gene exon 2  to the upstream of the H2-Ea-ps gene  exon 1 were knocked out to obtain H2-Ab1、H2-Aa、H2-Eb1、H2-Eb2、H2-Ea-ps knockout mouse models.Also, B2m gene was knocked out. These MHC class I and II molecule-deficient mice were on the NMG genetic background and also lacked cell surface expression of both class II-A and class II-E MHC proteins and B2m of class I.

Mice

Prss29-Flox

Strain Name：B6;129S-Prss29tm1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-00087

These mice carry loxP sites flanking exon 2. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

Hmgb2-Flox

Strain Name：C57BL/6Smoc-Hmgb2tm1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-190073

These mice carry loxP sites flanking exon 2-5 of Hmgb2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Hmgb2 gene.

Mice

Scgb3a2-IRES-Cre

Strain Name：C57BL/6Smoc-Scgb3a2em1(IRES-Cre-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-210127

IRES-Cre-polyA expression cassette was knocked into the Scgb3a2 gene.

Mice

Aqp5-Cre

Strain Name：C57BL/6Smoc-Aqp5em1(iCre-WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200062

A iCre-WPRE-polyA expression cassette was knocked into the Aqp5 gene start codon site.

Mice

Sumf2-Flox

Strain Name：B6;129S-Sumf2tm1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-00017

An frt-neo-frt cassette was inserted after exon 3 and loxP sites was inserted before exon 3 and after the neo cassette. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of

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