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P53 CKO Mouse Model

p53 knockout p53 knockout mice p53 gene

Our own-developed mouse model of p53 conditional knockout (p53-CKO) can be mated with mice carrying tissue-specific Cre expression to obtain mice with homozygous deletion of p53 in specific tissues or cells. These mice can be used for tumorigenesis and tumor mechanistic studies.

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Fibrosis

liver fibrosis model

The mouse liver fibrosis model can be generated by surgery or drug induction, which can be used to study the role of genes and proteins in the development of liver fibrosis, to explore the mechanisms underlying liver fibrosis, and to carry out drug efficacy evaluations.

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Rb1 CKO Mouse Model

With the ability to avoid the risk of death caused by homozygous and systemic knockout, our own-developed Rb1 conditional knockout mice (Rb1-CKO) can be used to study cancer, cell cycle or aging.

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Brca1 CKO Mouse Model

Our own-developed Brca1 conditional knockout mice (Brca1-CKO) can be used to study breast cancer.

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