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How do I breed conventional knockout mice or genetically mutated mice? How do I choose control mice for experiments?

genetically mutated neo gene phenotype definition

Gene Expression/Protein Analysis

protein expression analysis Gene expression analysis

Shanghai Model Organisms provides high-quality gene and protein expression analysis services, including RT-PCR, real time PCR, and Western blot, with accurate experimental results that can be used for publication.

Pathological Analysis

Pathological analysis H&E staining

Shanghai Model Organisms can analyze morphological and pathological changes in various animal tissues.

Phenotyping

mouse phenotype mouse phenotype database gene phenotype

Provide blood analysis, image analysis, pathology analysis, behavior analysis etc.

表現型分析

血液検査、画像分析、組織病理形態学的分析、行動学的研究、代謝学的分析などを提供することができます。

표현형 분석

혈액 검사, 영상 분석, 조직 병리 형태 분석, 행동 연구, 대사 분석 등을 제공합니다.

Mouse

transgenic mice mouse model editing mouse

Mice have long been the prime choice for model organisms. In more than 100 years, mice have been widely used by researchers in the fields of physiology, pathology, pharmacology, toxicology, and behavioral science. With the establishment of gene targeting technology, many researchers have made their way to the Nobel Prize.

Structure Analysis of Antigen and Antibody

e-BLOT Innovative Western Blot Imaging System

Osteoporosis

osteoporosis gene osteoporosis diseases Tnfrsf11b

Tnfrsf11b (Opg) knockout mice were generated through homologous recombination and supplied by Shanghai Research Center for Model Organisms. This mouse model, which is referred to as the "osteoporotic mouse", shows a typical phenotype of osteoporosis and arterial calcification, and Therefore, this animal model is ideal for drug screening and evaluation for the treatment of "human osteoporosis", in gene therapy of osteoporosis, as well as in the research on the mechanisms of interaction between osteoclasts and osteoblasts.