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Prkaa2-KO

Strain Name：C57BL/6Smoc-Prkaa2^em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-191108

Exon 2 of Prkaa2 gene was deleted to generate Prkaa2 knockout mice.

Prkaa2-Flox

Strain Name：C57BL/6Smoc-Prkaa2^{em1(flox)Smoc}
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200210

These mice carry loxP sites flanking exon 2 of Prkaa2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Prkaa2 gene.

Prkag2-KO

Strain Name：C57BL/6Smoc-Prkag2^em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191111

Exon 3 of Prkag2 gene was deleted to generate Prkag2 knockout mice.

Pro-survival and anti-inflammatory roles of NF-κB c-Rel in the Parkinson's disease models.

Model Organisms：Mouse Product & Service：c-Rel-luc Research field：parkinson

parkinson

The deficiency of NRSF/REST enhances the pro-inflammatory function ofastrocytes in a model of Parkinson's disease

Model Organisms：Mouse Product & Service：NRSF Research field：Parkinson

Parkinson

CNTNAP4 deficiency in dopaminergic neurons initiates parkinsonian phenotypes

Model Organisms：Mouse Product & Service：Cntnap4 Research field：parkinson

parkinson

These Mice Are About to Go Viral Because of the Nobel Prize!

microRNA (miRNA) microRNA mouse models Nobel Prize microRNA discovery genetically engineered mice miRNA in gene regulation miRNA therapeutics miRNA in cancer research customized mouse models contract research organization (CRO) preclinical drug discovery

The 2024 Nobel Prize in Physiology or Medicine awarded to Victor Ambros and Gary Ruvkun for their discovery of microRNA (miRNA) highlights its revolutionary role in gene regulation and disease treatment. This article explores miRNA's impact on neuroscience, cancer, and cardiovascular research. GenoBioTX offers advanced microRNA mouse models and customized genetic solutions, empowering researchers with essential tools to drive innovation in miRNA studies and therapeutic developments.

Nervous System

neuropsychiatric disorder models parkinson's disease models

The model of nerve injury induced by surgery or drugs can be used to study the mechanism of nerve injury and to evaluate drug efficacy.

Surgical & Preconditioning Services