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Models

About 24 results
Mice

Trp53-KO(2)

Strain Name：C57BL/6Smoc-Trp53em5Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191203

Exon 5-7 of Trp53 gene was deleted to generate Trp53 knockout mice.

Mice

Trp53-KO

Strain Name：B6.129-Trp53tm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00011

A neo cassette replaces exons 2-11,including the start codon,of Trp53 (transformation related protein 53).Null homozygotes show high, early-onset tumor incidence;some have persistent hyaloid vasculature and cataracts.

Mice

Irf5-Flox

Strain Name：C57BL/6Smoc-Irf5em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-200191

These mice carry loxP sites flanking exon 2 of Irf5 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Irf5 gene.

Mice

Dgcr8-Flox

Strain Name：C57BL/6Smoc-Dgcr8em1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200157

These mice carry loxP sites flanking exon 3 of Dgcr8 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Dgcr8 gene.

Mice

Pidd1-KO

Strain Name：C57BL/6Smoc-Pidd1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191165

Exon 3-6 of Pidd1 gene was deleted to generate Pidd1 knockout mice.

Mice

Pml-KO

Strain Name：C57BL/6Smoc-Pmlem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190619

Exon 2 of Pml gene was deleted to generate Pml knockout mice.

Mice

Trp53-Flox

Strain Name：C57BL/6Smoc-Trp53tm2(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-18005

These Trp53 flox mice possess loxP sites flanking exons 5-7 via ESC targeting. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

hTP53(2)

Strain Name：C57BL/6Smoc-Trp53tm1(hTP53)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-225052

The endogenous mouse Trp53 gene was replaced by human TP53 gene.

Mice

Trp53-R172H

Strain Name：C57BL/6Smoc-Trp53em4(R172H)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18028

These mice carry a p.R172H mutation of Trp53 gene.

Mice

Trp53-FSF-R270H

Strain Name：C57BL/6Smoc-Trp53tm(Frt-Stop-Frt-R270H)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-210364

These mice carry a p.R270H conditional mutation of Trp53 gene.

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