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Models

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Mice

pTRE-Nrg1-Tg

Strain Name:C57BL/6Smoc-Tg(tetO-HA-Nrg1-pA)
Strain State:Embryo cryopreservation | Cat. NO.:NM-TG-200006

TRE promoter-HA-NRG1 is transferred into the mouse genome via transgene technology,this strain is Nrg1 overexpression induced by tetracycline

Mice

C57BL/6

Strain Name:C57BL/6
Strain State:Repository Live | Cat. NO.:SM-001
Validation Data:Presence

It was the first mouse strain to have its genome sequenced. With black coat color, it is recognized as the "standard" inbred strain and provides genetic background for numerous mutant genes. It is characterized by stable strain properties, ease of breeding, uniform stress responses, and high precision in experimental results.

Mice

R26-CAG-FLEX-Zbp1-Mouse-L-3xFLAG

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-loxP-STOP-lox2272-3xFLAG-Zbp1-Mouse-L-Kozak-loxP-lox2272-WPRE-bGH-pA)Smoc
Strain State:Developing | Cat. NO.:NM-KI-250273

The CAG-loxP-STOP-lox2272-3xFLAG-Zbp1-Mouse-L-Kozak-loxP-lox2272-WPRE-bGH-pA expression cassette was knocked into the R26 locus.

Mice

Ncr1-2A-Cre

Strain Name:C57BL/6Smoc-Ncr1em2(2A-iCre)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-190027
Validation Data:Presence

A 2A-iCre expression cassette was knocked into the Ncr1 gene stop codon site.

Mice

Ncr1-IRES-mtagBFP2-Luc

Strain Name:C57BL/6Smoc-Ncr1em5(IRES-mtagBFP-luciferase)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200030
Validation Data:Presence

A IRES-mtagBFP-luciferase expression cassette was knocked into the Ncr1 gene stop codon site.

Mice

hPD-1

Strain Name:C57BL/6Smoc-Pdcd1tm1(hPDCD1) /Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00015
Validation Data:Presence  |  Publications:1piece

The endogenous mouse Pdcd1 gene was replaced by human PDCD1(PD-1) gene .

Mice

hC3

Strain Name:C57BL/6Smoc-C3tm1(hC3)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000079
Validation Data:Presence

The endogenous mouse C3 gene was replaced by human C3 gene.

Mice

hPCSK9

Strain Name:C57BL/6Smoc-Pcsk9tm2(hPCSK9)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00075
Validation Data:Presence  |  Publications:1piece

The endogenous mouse Pcsk9 gene was replaced by human PCSK9 gene .

Mice

hIL17A/hIL17F

Strain Name:C57BL/6Smoc-Il17atm1(hIL17A)Il17fem2(hIL17F)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-200281
Validation Data:Presence

The endogenous mouse Il17a&Il17f genes were replaced by human IL17A&IL17F gene.

Mice

hTP53(2)

Strain Name:C57BL/6Smoc-Trp53tm2(hTP53)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-225052
Validation Data:Presence

The endogenous mouse Trp53 gene was replaced by human TP53 gene.

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