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Models

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Mice

pTRE-Nrg1-Tg

Strain Name:C57BL/6Smoc-Tg(tetO-HA-Nrg1-pA)
Strain State:Embryo cryopreservation | Cat. NO.:NM-TG-200006

TRE promoter-HA-NRG1 is transferred into the mouse genome via transgene technology,this strain is Nrg1 overexpression induced by tetracycline

Mice

C57BL/6

Strain Name:C57BL/6Smoc
Strain State:Repository Live | Cat. NO.:SM-001

C57BL/6 mice have a high reproductive capacity, a long life span, and a low tumor susceptibility. Male mice are aggressive and fight frequently. Diet can cause obesity, type II diabetes, and atherosclerosis in these mice. The C57BL/6 mouse is the first to have its entire genome sequenced. It is the most extensively used inbred mouse strain as a genetic basis for congenic and mutant mice. It is also used in genetics, metabolism, immunology, neurology, behavioral research, pharmacodynamics, and medication safety evaluation.

Mice

R26-CAG-LSL-Zbp1-Mouse-L-3xFLAG-bGH

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-Kozak-Zbp1-Mouse-L-3xFLAG-WPRE-bGH-pA)Smoc
Strain State:Developing | Cat. NO.:NM-KI-241596

The CAG-LSL-Kozak-Zbp1-Mouse-L-3xFLAG-WPRE-bGH-pA expression cassette was knocked into the R26 locus.

Mice

R26-CAG-FLEX-Zbp1-Mouse-L-3xFLAG

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-loxP-STOP-lox2272-3xFLAG-Zbp1-Mouse-L-Kozak-loxP-lox2272-WPRE-bGH-pA)Smoc
Strain State:Developing | Cat. NO.:NM-KI-250273

The CAG-loxP-STOP-lox2272-3xFLAG-Zbp1-Mouse-L-Kozak-loxP-lox2272-WPRE-bGH-pA expression cassette was knocked into the R26 locus.

Mice

Ncr1-2A-Cre

Strain Name:C57BL/6Smoc-Ncr1em2(2A-iCre)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-190027

A 2A-iCre expression cassette was knocked into the Ncr1 gene stop codon site.

Mice

Ncr1-IRES-mtagBFP2-Luc

Strain Name:C57BL/6Smoc-Ncr1em5(IRES-mtagBFP-luciferase)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200030

A IRES-mtagBFP-luciferase expression cassette was knocked into the Ncr1 gene stop codon site.

Mice

hPD-1

Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1) /Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00015

The endogenous mouse Pdcd1 gene was replaced by human PDCD1(PD-1) gene .

Mice

hC3

Strain Name:C57BL/6Smoc-C3em1(hC3)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000079

The endogenous mouse C3 gene was replaced by human C3 gene.

Mice

hPCSK9

Strain Name:C57BL/6Smoc-Pcsk9em2(hPCSK9)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00075

The endogenous mouse Pcsk9 gene was replaced by human PCSK9 gene .

Mice

hTP53(2)

Strain Name:C57BL/6Smoc-Trp53tm1(hTP53)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-225052

The endogenous mouse Trp53 gene was replaced by human TP53 gene.

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