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Models

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Mice

HLA-E1.3/B2M(2)

Strain Name：C57BL/6JSmoc-B2mem1(hB2M-linker-HLA-E*0103/H2-D1)Smoc
Strain State：Developing | Cat. NO.：NM-HU-261706

The endogenous mouse B2m gene was replaced by human B2M gene.

Mice

hF3(2)

Strain Name：C57BL/6JSmoc-F3tm1(hF3)Smoc
Strain State：Developing | Cat. NO.：NM-HU-261707

The endogenous mouse F3 gene was replaced by human F3 gene.

Mice

hAPOE4-Flox-hAPOE2

Strain Name：C57BL/6J-Apoeem1(hAPOE4-Flox-hAPOE2)Smoc
Strain State：Developing | Cat. NO.：NM-HU-261708

The endogenous mouse Apoe gene was replaced by human APOE gene.

Mice

hSCN8A

Strain Name：C57BL/6JSmoc-Scn8atm1(hSCN8A)Smoc
Strain State：Developing | Cat. NO.：NM-HU-261791

The endogenous mouse Scn8a gene was replaced by human SCN8A gene.

Mice

hCRHR2

Strain Name：C57BL/6JSmoc-Crhr2tm1(hCRHR2)Smoc
Strain State：Developing | Cat. NO.：NM-HU-261792

The endogenous mouse Crhr2 gene was replaced by human CRHR2 gene.

Mice

Fcgr1-KO

Strain Name：C57BL/6Smoc-Fcgr1em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18033

The Fcgr1 knockout mouse model was obtained by knocking out all coding regions of mouse Fcgr1 gene.

Mice

hCD40

Strain Name：C57BL/6Smoc-Cd40tm1(hCD40) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00076
Validation Data：Presence

The endogenous extracellular mouse Cd40 gene was replaced by the extracellular region of human CD40 gene.

Mice

hB7H4

Strain Name：C57BL/6Smoc-Vtcn1tm1(hVTCN1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190004

This VTCN1 humanized mouse model was established by replacing the mouse Vtcn1 gene with the human VTCN1. While hB7H4(2)(Stock No.NM-HU-190075) mice function similarly to hB7H4 mice,for more detailed information please contact our technical advisor.

Mice

hBTLA(2)

Strain Name：C57BL/6Smoc-Btlatm2(hBTLA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190040
Validation Data：Presence

Extracellular domain of mouse Btla gene was replaced by human BTLA gene. While hBTLA mice(Stock No.NM-HU-18014）have been pulled from shelves for some reasons.

Mice

hTLR9

Strain Name：C57BL/6Smoc-Tlr9tm1(hTLR9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18016
Validation Data：Presence

This TLR9 humanized mouse model was established by replacing the mouse Tlr9 gene exon2 with the human TLR9 corresponding sequence by homologous recombination.

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