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Models

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Mice

pTRE-Nrg1-Tg

Strain Name：C57BL/6Smoc-Tg(tetO-HA-Nrg1-pA)
Strain State：Embryo cryopreservation | Cat. NO.：NM-TG-200006

TRE promoter-HA-NRG1 is transferred into the mouse genome via transgene technology，this strain is Nrg1 overexpression induced by tetracycline

Mice

C57BL/6

Strain Name：C57BL/6
Strain State：Repository Live | Cat. NO.：SM-001
Validation Data：Presence

It was the first mouse strain to have its genome sequenced. With black coat color, it is recognized as the "standard" inbred strain and provides genetic background for numerous mutant genes. It is characterized by stable strain properties, ease of breeding, uniform stress responses, and high precision in experimental results.

Mice

Cdkn2a/Cdkn2b-KO(p15/p16/p19-KO)

Strain Name：C57BL/6Smoc-Cdkn2aemCdkn2bem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-241617

The p15/p16/p19-KO mouse model was established by knocking out all genomic regions between exon1 of the p15 gene and exon1 of the p16 gene.

Mice

Ldoc1-KO

Strain Name：C57BL/6Smoc-Ldoc1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-252160

The exon 1 of Ldoc1 gene was deleted to generate Ldoc1 knockout mouse. This gene overlaps with the ENSMUSG00000124784(lncRNA) gene at the genomic locus and may impact the function of the overlapping gene.

Mice

Cdkn2a/Cdkn2b-Flox(p15/p16/p19-Flox)

Strain Name：C57BL/6Smoc-Cdkn2a/Cdkn2bem1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-235093

The p15/p16/p19-Flox mouse model was obtained by inserting a loxp site upstream of the Cdkn2b gene exon 1 and another loxP site downstream of the Cdkn2a(p16) gene exon 1. The flox region of these strains contains the entire genomic region between exon1 of the p15 gene and exon1 of the p16 gene.

Mice

R26-CAG-FLEX-Zbp1-Mouse-L-3xFLAG

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-loxP-STOP-lox2272-3xFLAG-Zbp1-Mouse-L-Kozak-loxP-lox2272-WPRE-bGH-pA)Smoc
Strain State：Developing | Cat. NO.：NM-KI-250273

The CAG-loxP-STOP-lox2272-3xFLAG-Zbp1-Mouse-L-Kozak-loxP-lox2272-WPRE-bGH-pA expression cassette was knocked into the R26 locus.

Mice

Ncr1-2A-Cre

Strain Name：C57BL/6Smoc-Ncr1em2(2A-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190027
Validation Data：Presence

A 2A-iCre expression cassette was knocked into the Ncr1 gene stop codon site.

Mice

Ncr1-IRES-mtagBFP2-Luc

Strain Name：C57BL/6Smoc-Ncr1em5(IRES-mtagBFP-luciferase)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200030
Validation Data：Presence

A IRES-mtagBFP-luciferase expression cassette was knocked into the Ncr1 gene stop codon site.

Mice

hPD-1

Strain Name：C57BL/6Smoc-Pdcd1tm1(hPDCD1) /Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00015
Validation Data：Presence  |  Publications：1piece

The endogenous mouse Pdcd1 gene was replaced by human PDCD1(PD-1) gene .

Mice

hC3

Strain Name：C57BL/6Smoc-C3tm1(hC3)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000079
Validation Data：Presence

The endogenous mouse C3 gene was replaced by human C3 gene.

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