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Models

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Mice

pTRE-Nrg1-Tg

Strain Name:C57BL/6Smoc-Tg(tetO-HA-Nrg1-pA)
Strain State:Embryo cryopreservation | Cat. NO.:NM-TG-200006

TRE promoter-HA-NRG1 is transferred into the mouse genome via transgene technology,this strain is Nrg1 overexpression induced by tetracycline

Mice

C57BL/6

Strain Name:C57BL/6Smoc
Strain State:Repository Live | Cat. NO.:SM-001

C57BL/6 mice have a high reproductive capacity, a long life span, and a low tumor susceptibility. Male mice are aggressive and fight frequently. Diet can cause obesity, type II diabetes, and atherosclerosis in these mice. The C57BL/6 mouse is the first to have its entire genome sequenced. It is the most extensively used inbred mouse strain as a genetic basis for congenic and mutant mice. It is also used in genetics, metabolism, immunology, neurology, behavioral research, pharmacodynamics, and medication safety evaluation.

Mice

Cdkn2a/Cdkn2b-KO(p15/p16/p19-KO)

Strain Name:C57BL/6Smoc-Cdkn2aemCdkn2bem1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-241617

The p15/p16/p19-KO mouse model was established by knocking out all genomic regions between exon1 of the p15 gene and exon1 of the p16 gene.

Mice

Cdkn2a/Cdkn2b-Flox(p15/p16/p19-Flox)

Strain Name:C57BL/6Smoc-Cdkn2a/Cdkn2bem1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-235093

The p15/p16/p19-Flox mouse model was obtained by inserting a loxp site upstream of the Cdkn2b gene exon 1 and another loxP site downstream of the Cdkn2a(p16) gene exon 1. The flox region of these strains contains the entire genomic region between exon1 of the p15 gene and exon1 of the p16 gene.

Mice

R26-CAG-LSL-Zbp1-Mouse-L-3xFLAG-bGH

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-Kozak-Zbp1-Mouse-L-3xFLAG-WPRE-bGH-pA)Smoc
Strain State:Developing | Cat. NO.:NM-KI-241596

The CAG-LSL-Kozak-Zbp1-Mouse-L-3xFLAG-WPRE-bGH-pA expression cassette was knocked into the R26 locus.

Mice

R26-CAG-FLEX-Zbp1-Mouse-L-3xFLAG

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-loxP-STOP-lox2272-3xFLAG-Zbp1-Mouse-L-Kozak-loxP-lox2272-WPRE-bGH-pA)Smoc
Strain State:Developing | Cat. NO.:NM-KI-250273

The CAG-loxP-STOP-lox2272-3xFLAG-Zbp1-Mouse-L-Kozak-loxP-lox2272-WPRE-bGH-pA expression cassette was knocked into the R26 locus.

Mice

Ncr1-2A-Cre

Strain Name:C57BL/6Smoc-Ncr1em2(2A-iCre)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-190027

A 2A-iCre expression cassette was knocked into the Ncr1 gene stop codon site.

Mice

Ncr1-IRES-mtagBFP2-Luc

Strain Name:C57BL/6Smoc-Ncr1em5(IRES-mtagBFP-luciferase)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200030

A IRES-mtagBFP-luciferase expression cassette was knocked into the Ncr1 gene stop codon site.

Mice

hPD-1

Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1) /Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00015

The endogenous mouse Pdcd1 gene was replaced by human PDCD1(PD-1) gene .

Mice

hC3

Strain Name:C57BL/6Smoc-C3em1(hC3)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000079

The endogenous mouse C3 gene was replaced by human C3 gene.

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