Welcome to Advanced Search

Models

About 599 results
Mice

R26-CAG-LSL-hSOS-F-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-loxp-Stop-loxp-SOS-F-IRES-tdTomato-WPRE-PA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200020

These mice harbor a SA-FRT-2xpolyA-CAG-FRT-loxp-Stop-loxp-SOS-F-IRES-tdTomato-WPRE-PA cassette in the Rosa26 locus generated by homologous recombination.

Mice

R26-CAG-LSL-hMLL-AF9-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpA-CAG-FRT-loxp-STOP-loxp-MLL-AF9-IRES-Luciferase-2A-tdTomato -WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190114

These mice harbor a SA-Frt-pA-CAG-Frt-LSL-MLL-AF9-IRES-Luc-2A-tdTomato-WPRE-pA cassette in the Rosa26 locus generated by homologous recombination.

Mice

Rag2-KO

Strain Name：C57BL/6Smoc-Rag2em2Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190429

Partial exon 3 of Rag2 gene was deleted to generate Rag2 knockout mice. Deletion of this region will cause frameshift and result in loss of function of mouse Rag2 gene.

Mice

Enpp1-KO

Strain Name：C57BL/6Smoc-Enpp1em2Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200618

Exon 2 of Enpp1 gene was deleted to generate Enpp1 knockout mice.

Mice

Foxj1-EGFP-CreERT2

Strain Name：C57BL/6Smoc-Foxj1em1(GFP-CreERT2-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200133

A GFP-CreERT2-polyA expression cassette was knocked into the Foxj1 gene start codon site.

Mice

hIL13/hIL4/hIL4R

Strain Name：C57BL/6Smoc-Il4tm3(hIL4)Il4ratm1(hIL4R)Il13em3(hIL13)Smoc
Strain State：Developing | Cat. NO.：NM-HU-251863

Based on the hIL4/hIL4R(NM-HU-2000106) strain, the endogenous mouse Il13 gene was replaced by human IL13 gene.

Mice

hCD3EDG/hTNFRSF10C-Tg(BALB/c)

Strain Name：BALB/cAnSmoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Tgtn(hTNFRSF10C)1Smoc
Strain State：Developing | Cat. NO.：NM-TG-251880

Based on the hCD3EDG(BALB/c) NM-HU-220122 strain, these transgenic mice harbor hTNFRSF10C expression cassettes.

Mice

Mir183/Mir96-KO

Strain Name：C57BL/6Smoc-Mir183emMir96em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-234774

Mir183 and Mir96 knockout mouse models were established by knockout transcripts of Mir183-201 and Mir96-201.

Mice

hOX40/hCTLA-4

Strain Name：C57BL/6Smoc-Tnfrsf4em3(hTNFRSF4)Ctla4em1(hCTLA4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00105

These mice are OX40 and CTLA4 double knockin mouse models which can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

Tnfrsf1a/Tnfrsf1b-KO

Strain Name：C57BL/6Smoc-Tnfrsf1aem1Smoc Tnfrsf1aem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18036

This strain is also called p55/p75-KO. The Tnfrsf1a and Tnfrsf1b double knockout mouse models were obtained by knocking out both exon 2-5 region of mouse Tnfrsf1a gene and exon2 of mouse Tnfrsf1b gene. Tnfrsf1a and Tnfrsf1b deletion (p55 and p75 deficiency) homozygous mice are viable and fertile, and these homozygous mice fail to bind TNF (tumor necrosis factor).

Email Back to top