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Imaging Analysis

Animal imaging micro CT

shanghai Model Organisms provides services for microCT and IVIS whole-body in vivo imaging/fluorescence quantitative analysis of small animals.

Pathological Analysis

Pathological analysis H&E staining

Shanghai Model Organisms can analyze morphological and pathological changes in various animal tissues.

Gene Expression/Protein Analysis

protein expression analysis Gene expression analysis

Shanghai Model Organisms provides high-quality gene and protein expression analysis services, including RT-PCR, real time PCR, and Western blot, with accurate experimental results that can be used for publication.

Behavioral Analysis

study of animal behavior behavioral analysis

Shanghai Model Organisms' rodent behavioral analysis platform is equipped with a variety of experimental instruments used to study the classical behaviors of mice. Shanghai Model Organisms can provide single-item or complete sets of mouse behavioral analysis to assist you with your research in neurology, physiology, drug development, and drug efficacy evaluation. The Noldus behavioral analysis system is used to more comprehensively and accurately reflect the neurological and mental states of mice.

Services

genetic engineering genetic animals genetic engineering examples

Shanghai Model Organisms offers a full range of model organism services, including model customization services, research-ready models, breeding, phenotyping and drug screening. Mouse, rat, zebrafish and C. elegans models are available to meet different research needs.

약물 효과 분석 및 평가

Shanghai Model Organisms Center, Inc.(사)는 약물 효과 평가 서비스는 U-GEMMs 리소스 라이브러리를 기반으로 하여 항염 면역, 항종양, 심혈관계, 호흡계, 대사성 질병 등 약물의 주요 약력학 연구를 수행할 수 있으며, 체내 실험, 메커니즘 검토 및 분자생물학 연구 등 서로 다른 수준의 연구 수요를 충족시켜 신약의 유효성과 안전성을 확립하고 국내외의 제약업체, 생물의학연구소, 신약개발센터, 고등교육기관의 신약 연구개발 기관 등에 전문적인 약력학 평가 서비스를 제공합니다.

Blood Analysis

Mouse serum mouse serum albumin

At Shanghai Model Organisms Center, we use an automatic biochemical analyzer to measure a specific chemical composition of serum according to the principle of photoelectric colorimetry. This can be used to assess liver and kidney functions or measure blood sugar, blood lipids, and electrolytes.

Drug Screening

drug screening high throughput screening for drug discovery

With a comprehensive model organisms service platform that generates the mouse, zebrafish and C. elegans models, Shanghai Model Organisms enables high-throughput drug screening as well as the evaluation and research on drug efficacy, thus accelerating drug development and achieving greater accuracy in the prediction of in vivo interactions.

Gene overexpression

gene overexpression gene overexpression protocol gene overexpression techniques

Generate a mouse model in which an exogenous gene is introduced and overexpressed. An overexpression model can be used to investigate gene functions, promoter functions, or model the pathogenesis of human disease. Depending on the method to introduce foreign DNA, a random transgenes or targeted conditional overexpression model can be created.

Excision and Regeneration of Tissue

liver regeneration subtotal gastrectomy

A mouse tissue regeneration model can be established by an operation of partial tissue excision. Such models can be used to study the changes in morphology, serology and metabolism during tissue regeneration, and hence lay the experimental foundation for studying the mechanisms regulating tissue regeneration.