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Models

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Mice

Rcvrn-Flox

Strain Name：C57BL/6Smoc-Rcvrnem1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of Rcvrn gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Rcvrn gene.

Mice

Rcvrn-KO

Strain Name：C57BL/6Smoc-Rcvrnem1Smoc
Strain State：Developing | Cat. NO.：TBD

Exon 1 of Rcvrn gene was deleted to generate Rcvrn knockout mice.

Mice

hIL4/hIL4RA/hKLK5

Strain Name：C57BL/6Smoc-Il4tm1(hIL4)Il4ratm1(hIL4RA)Klk5tm1(hKLK5)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-251787

Based on the hIL4/hIL4R(NM-HU-2000106) strain, the endogenous murine Klk5 gene was replaced with the human KLK5 gene through homologous recombination.

Mice

hLDLR-delta ARE

Strain Name：C57BL/6Smoc-hLDLRtm1(delta ARE)Smoc
Strain State：Developing | Cat. NO.：NM-HU-253731

This product was derived by deleting a certain region in the 3'UTR part based on the NM-HU-230148 (hLDLR) mice.

Mice

hβA

Strain Name：C57BL/6Smoc-Hbb-bs＆Hbb-bttm1(hHBG1，hHBB)Smoc
Strain State：Developing | Cat. NO.：NM-HU-253365

By using homologous recombination, the mouse Hbb-bs and Hbb-bt genes were subjected to humanization modification (the human genes being: HBA1 and HBA2).

Mice

hβS

Strain Name：C57BL/6Smoc-Hbb-bs＆Hbb-bttm1(hHBG1,hHBB-E7V)Smoc
Strain State：Developing | Cat. NO.：NM-HU-253366

By using homologous recombination, the mouse Hbb-bs and Hbb-bt genes were subjected to humanization modification (the human genes being: HBG1 and HBB).

Mice

Hspa1a-Flox（Hspa1b-Flox）/Hspa1b-Flox

Strain Name：C57BL/6Smoc-Hspa1aem1(flox)Hspa1bem1(flox)Hspa1bem1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-XA-253395

The Hspa1a-Flox（Hspa1b-Flox） (NM-CKO-253326) was crossed with Hspa1b-Flox(NM-CKO-232189) to generate Hspa1a-Flox（Hspa1b-Flox）/Hspa1b-Flox mice.

Mice

Hspa1a-Flox（Hspa1b-Flox）

Strain Name：C57BL/6Smoc-Hspa1aem1(flox)SmocHspa1bem1(flox)Smoc
Strain State：Developing | Cat. NO.：NM-CKO-253326

Perform editing on the existing strain Hspa1b-Flox,these mice carry loxP sites flanking exon 1 of Hspa1a gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Hspa1a gene.

Mice

hIL13/hIL4/hIL4R

Strain Name：C57BL/6Smoc-Il4tm3(hIL4)Il4ratm1(hIL4R)Il13tm3(hIL13)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-251863

Based on the hIL4/hIL4R(NM-HU-2000106) strain, the endogenous mouse Il13 gene was replaced by human IL13 gene.

Mice

hCD3EDG/hTNFRSF10C-Tg(BALB/c)

Strain Name：BALB/cAnSmoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Tgtn(hTNFRSF10C)1Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-251880

Based on the hCD3EDG(BALB/c) NM-HU-220122 strain, these transgenic mice harbor hTNFRSF10C expression cassettes.

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