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Mice

Npr1-LSL-2A-DTR-2A-tdTomato

Strain Name:C57BL/6Smoc-Npr1em(loxp-stop-loxp-P2A-DTR-T2A-tdTomato)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-220051

loxp-stop-loxp-P2A-DTR-T2A-tdTomato expression cassette was knocked into the Npr1 gene stop codon site.

Mice

Cd34-LSL-DreERT2

Strain Name:C57BL/6Smoc-Cd34tm1(loxP-STOP-loxP-Kozak-DreERT2-WPRE-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-231444

The loxP-STOP-loxP-Kozak-DreERT2-WPRE-pA expression cassette was knocked into the Cd34 gene start codon site.

Mice

Cthrc1-LSL-2A-Dre

Strain Name:C57BL/6Smoc-Cthrc1em1(loxP-CC-STOP-loxP-CC-2A-Dre)Smoc
Strain State:Developing | Cat. NO.:NM-KI-261018

The loxP-CC-STOP-loxP-CC-2A-Dre expression cassette was knocked into the Cthrc1 gene stop codon site.

Mice

Spp1-LSL-DTR-2A-EGFP

Strain Name:C57BL/6Smoc-Spp1em1(loxP-STOP-loxP-Kozak-DTR-2A-EGFP-WPRE-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-234008

The loxP-STOP-loxP-Kozak-DTR-2A-GFP-WPRE-pA expression cassette was knocked into the Spp1 gene start codon site.

Mice

Pdcd1lg2-LSL-2A-DTR-2A-EGFP

Strain Name:C57BL/6Smoc-Pdcd1lg2em1(loxP-STOP-loxP-P2A-DTR-T2A-EGFP-WPRE-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-231495

The loxP-STOP-loxP-P2A-DTR-T2A-EGFP-WPRE-pA expression cassette was knocked into the Pdcd1lg2 gene stop codon site.

Mice

Slco1c1-2A-CreERT2

Strain Name:C57BL/6Smoc-Slco1c1em1(2A-CreERT2)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200262
Validation Data:Presence

2A-CreERT2 expression cassette was knocked into the Slco1c1 gene stop codon site. Slco1c1 encodes a member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of thyroid hormones in brain tissues. This protein has particularly high affinity for the thyroid hormones thyroxine, tri-iodothyronine and reverse tri-iodothyronine. When Slco1c1-2A-CreERT2 mice are bred with mice containing loxP-flanked sequence, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the floxed sequences in SLCO1C1 positive cells.

Mice

R26-CAG-LSL-dCas9-IRES-EGFP

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-Avi tag-dCas9-IRES-EGFP-WPRE-pA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-18031

A CAG promoter-loxp-stop-loxp-Avi tag-dCas9-IRES-EGFP-WPRE-polyA expression cassette was inserted at the Rosa26 locus site.

Mice

R26-CAG-LSL-hTERT-IRES-Luc-2A-EGFP

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-LSL-V5-TERT-IRES-Luciferase-2A-EGFP-WPRE-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-18035

A CAG promoter-loxp-stop-loxp-V5-TERT-IRES-Luciferase-2A-EGFP-WPRE-polyA expression cassette was inserted at the Rosa26 locus site.

Mice

Axin2-CreERT2

Strain Name:C57BL/6Smoc-Axin2em1(CreERT2-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200109
Validation Data:Presence

A CreERT2-pA expression cassette was knocked into the Axin2 gene start codon site. As Axin2 is an intracellular protein, it is essential for identifying a surface marker for stem cell purification. When these Axin2-CreERT2 mice are bred with mice containing a loxP-flanked sequence of interest, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the flanked sequences in Axin2 expressing cells.

Mice

Prox1-IRES-CreERT2

Strain Name:C57BL/6Smoc-Prox1em1(IRES-CreERT2-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200119
Validation Data:Presence

A IRES-CreERT2-pA expression cassette was knocked into the Prox1 gene stop codon site. Prox1 encodes a transcription factor (prospero-related homeobox 1) that is necessary for the formation and maintenance of lymphatic vessels. When Prox1-IRES-CreERT2 mice are bred with mice containing loxP-flanked sequence, tamoxifen-inducible Cre-mediated recombination will result in deletion of the floxed sequences in PROX1positive cells.

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