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Expression of hepatitis B virus proteins in transgenic mice alters lipid metabolism and induces oxidative stress in...

Model Organisms：小鼠 Product & Service：HBV-Tg Research field：Expression of hepatitis B virus proteins in transgenic mice

LECT2, a Ligand for Tie1, Plays a Crucial Role in Liver Fibrogenesis

Model Organisms：Mouse Product & Service：Lect2-cre Research field：Liver

These Mice Are About to Go Viral Because of the Nobel Prize!

microRNA (miRNA) microRNA mouse models Nobel Prize microRNA discovery genetically engineered mice miRNA in gene regulation miRNA therapeutics miRNA in cancer research customized mouse models contract research organization (CRO) preclinical drug discovery

The 2024 Nobel Prize in Physiology or Medicine awarded to Victor Ambros and Gary Ruvkun for their discovery of microRNA (miRNA) highlights its revolutionary role in gene regulation and disease treatment. This article explores miRNA's impact on neuroscience, cancer, and cardiovascular research. GenoBioTX offers advanced microRNA mouse models and customized genetic solutions, empowering researchers with essential tools to drive innovation in miRNA studies and therapeutic developments.

How long does it take to obtain a genetically engineered mouse model listed in the repository?

What measures to take if the mice are having difficulty breeding?

pregnant mice circadian rhythm tocopherol

What is the reason to use sentinel mice?

sentinel mice BALB/c mice C57BL/6 mice

Excision and Regeneration of Tissue

liver regeneration subtotal gastrectomy

A mouse tissue regeneration model can be established by an operation of partial tissue excision. Such models can be used to study the changes in morphology, serology and metabolism during tissue regeneration, and hence lay the experimental foundation for studying the mechanisms regulating tissue regeneration.

Surgical & Preconditioning Services

Gene tracking

marker gene gene tracking

Gene tracers are an important application for genetically engineered mice. Through gene knock-in, exogenous tracer genes were knocked into endogenous genes, enabling labeling and tracing of genes.

Lineage tracing

lineage tracing genetic lineage tracing genetic fate mapping

Genetic lineage tracing is a commonly used and the most effective method for studying the origin and fate of specific cell types. The construction of genetically engineered mouse model is the most important step in the lineage tracing technique.