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Perivenous stellate cells are the main source of myofibroblasts and cancer‐associated‐fibroblasts formed after...

Model Organisms：Mouse Product & Service：Col1a1-e(Kozak-BFP-WPRE-pA) Research field：Liver tumor

Regional delivery of mesothelin-targeted chimeric antigen receptor T-cell effectively and safely targets colorectal...

Model Organisms：小鼠 Product & Service：- Research field：

Disruption of palladin leads to defects in definitive erythropoiesis by interfering with erythroblastic island...

Model Organisms：小鼠 Product & Service：Palld Research field：Development

肝脏红细胞

Expression of hepatitis B virus proteins in transgenic mice alters lipid metabolism and induces oxidative stress in...

Model Organisms：小鼠 Product & Service：HBV-Tg Research field：Expression of hepatitis B virus proteins in transgenic mice

LECT2, a Ligand for Tie1, Plays a Crucial Role in Liver Fibrogenesis

Model Organisms：Mouse Product & Service：Lect2-cre Research field：Liver

These Mice Are About to Go Viral Because of the Nobel Prize!

microRNA (miRNA) microRNA mouse models Nobel Prize microRNA discovery genetically engineered mice miRNA in gene regulation miRNA therapeutics miRNA in cancer research customized mouse models contract research organization (CRO) preclinical drug discovery

The 2024 Nobel Prize in Physiology or Medicine awarded to Victor Ambros and Gary Ruvkun for their discovery of microRNA (miRNA) highlights its revolutionary role in gene regulation and disease treatment. This article explores miRNA's impact on neuroscience, cancer, and cardiovascular research. GenoBioTX offers advanced microRNA mouse models and customized genetic solutions, empowering researchers with essential tools to drive innovation in miRNA studies and therapeutic developments.

How long does it take to obtain a genetically engineered mouse model listed in the repository?

What measures to take if the mice are having difficulty breeding?

pregnant mice circadian rhythm tocopherol

What is the reason to use sentinel mice?

sentinel mice BALB/c mice C57BL/6 mice

Fibrosis

liver fibrosis model

The mouse liver fibrosis model can be generated by surgery or drug induction, which can be used to study the role of genes and proteins in the development of liver fibrosis, to explore the mechanisms underlying liver fibrosis, and to carry out drug efficacy evaluations.